The expression of inhibitory receptors on leukocytes in allergic rhinitis. (EXIRA-study)

Completed

• Conditions: allergic rhinitis; hay fever; 10001708

• Registration Number: NL-OMON36104
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 84

Inclusion Criteria

Patients with allergic rhinitis
-Age 18-35 years
-No severe co-morbidity, other than allergic symptoms
-Proven allergic rhinitis (based on clinical evaluation of a medical doctor or with positive RAST) experiencing at least nasal symptoms
-Suffering from outdoor allergies (hay fever, pollen, weeds, grass) or indoor allergies (mold, dust, dust mite) or pet allergies.
- Good understanding of the Dutch language
- Willingness to receive a member of the investigation team in the house of the participant;Controls
-Healthy individuals 18-35 years with a runny nose

Exclusion Criteria

-Any severe comorbidity
-Any other infection during the department visit
-Immunological nasal disease (Churg-Strauss syndrome, Sjögren*s syndrome, systemic lupus erythematosus, sarcoidosis, Wegener*s granulomatosis)
-Use of nasal corticosteroid spray 1 month or less prior during the hospital visit.
-Use of oral corticosteroids 1 month or less prior during the hospital visit.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified