Investigating the impact of coronavirus infection (COVID-19) on cardiovascular injury using multiple imaging methods
- Conditions
- Cardiovascular injury (primary inflammatory, ischaemic, or secondary to systemic pathophysiology) in the context of COVID-19 infectionCirculatory SystemCardiovascular disease, COVID-19 (SARS-CoV-2 infection)
- Registration Number
- ISRCTN12154994
- Lead Sponsor
- The Aga Khan University Hospital
- Brief Summary
2020 Preprint results in https://doi.org/10.21203/rs.3.rs-77405/v2 non-peer-reviewed protocol in preprint (added 17/03/2021) 2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33964872/ (added 11/05/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36102258/ (added 15/09/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
1. COVID19 positive test within the previous 2 weeks (can be extended to 4 weeks at the investigator's discretion)
2. Aged =18 years
1. Prior diagnosis of myocardial infarction
2. Requiring invasive or non-invasive ventilation
3. Previous coronary revascularisation or cardiac surgery
4. Unable to undergo CT or CMR scanning, due to severe renal failure (estimated glomerular filtration rate <30 ml/min) or major allergy to iodinated contrast media /gadolinium
5. Pregnancy or breast feeding
6. Unable to give informed consent
7. Contraindication to imaging example metal fragments in the eye
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method