The efficacy and mechanism of Yishen Paidu Formula for chronic kidney disease (stage 4 to 5): a pilot study.
- Conditions
- Chronic kidney disease
- Registration Number
- ITMCTR2200006574
- Lead Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
? Aged =18 years;
? Chronic kidney disease stage 4 to 5 (non-dialysis) patients.
? Patients agreed to participate in the study with inform consent.
? Pregnant women or patients in lactating;
? Patients with hyperkalemia, acute heart failure and other conditions which require initiation of dialysis;
? Patients who are taking glucocorticoids or immunosuppressants;
? Patients with inflammatory bowel disease, or patients with severe primary diseases such as active malignant tumor and gastrointestinal bleeding, or patients who cannot cooperate with treatment such as mental illness.
? Patients with acute infection or using antibiotics
? Patients who are taking probiotics, probiotics and other drugs that affect intestinal flora
? Patients who are allergy to the drugs used in the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method estimated glomerular rate filtering;
- Secondary Outcome Measures
Name Time Method serum albumin;intestinal flora sequencing;blood urea nitrogen;urine protein creatinine ratio;uremia toxin;haemoglobin;blood creatinine;