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URO-BCG-4 : Bladder Tumors Immunotherapy

Completed
Conditions
Bladder Cancer
Registration Number
NCT00213655
Lead Sponsor
University Hospital, Rouen
Brief Summary

Evaluation of maintenance BCG immunotherapy (dose 27 mg) in superficial bladder tumors. Two randomized arms (every 3 or 6 months) will be studied for a population of 300 patients.

Detailed Description

BCG maintenance immunotherapy 1/3 dose : 27 mg two randomized arms : 3 or 6 months for 36 months clinical side effects according to OMS score efficacy regarding recurrence : cytology and cystoscopy PSA, leucocyturia and N-ramp gene evaluation

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
146
Inclusion Criteria
  • Ta and T1 bladder tumors
Exclusion Criteria
  • BCG contra-indications

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Tumoral responseMonth 36

Tumoral response assessed at M36

Secondary Outcome Measures
NameTimeMethod
Tumoral responseMonth 24

Tumoral response assessed at M24

Trial Locations

Locations (1)

Charles Nicolle, University Hospital

🇫🇷

Rouen, France

Charles Nicolle, University Hospital
🇫🇷Rouen, France

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