Evaluation of the effect of oral trehalose in patients with traumatic head injury in IC
- Conditions
- Trauma / head injury. Intracranial injury that involves brain damage.
- Registration Number
- IRCT20210508051223N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Critically ill TBI patients admitted to ICU
Stable hemodynamic and metabolic conditions in the first 24-48 h
GCS=7
Having antral feeding
Lack of intolerance to food sources containing trehalose such as mushroom
Willingness to cooperate and sign the informed consent form after full knowledge of the objectives and method of the study by the individual or legal guardian
18?year = age?=?65?year
Patients with head trauma who have been on Per Os (NPO) for more than 48 hours (not allowed to receive food).
Head trauma patients receiving parenteral nutrition (TPN).
Patients who are transferred from other ICUs after 1 week.
Having a history of cancer, autoimmune diseases, and congenital metabolic diseases.
Pregnancy and lactation.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method