Pregabalin tablet for Postoperative pain in breast suregry patients

Not Applicable

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2022/12/048101
• Lead Sponsor: Dr. Pooja K Subbiah

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) ASA (American Society of Anaesthesiologist) physical status 1 and 2 (ASA 1- healthy patients, ASA 2- Patients with mild to moderate systemic disease which is well under control)

2)Patients for MRM (Modified Radical Mastectomy) +/- Axillary clearance

3)Patients for breast conservative surgery.

Exclusion Criteria

1) Allergy to Pregabalin

2)Patients not willing to participate in the study.

3)Patients having history of vertigo, dizziness.

4)ASA physical status 3 and above(ASA 3- Patients with severe systemic disease, ASA 4-Patients with severe systemic disease that is a constant threat to life, ASA 5- moribund patient who is not expected to survive, ASA 6-declared brain dead patient.)

5)Patients coming for Redo surgery.

6)Patients who have received radiation

7)Patients allergic to Inj. Diclofenac

8) Patients already on Tab.Pregabalin.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure postoperative pain by VAS score and analgesic requirement among breast cancer patients receiving either Capsule Pregabalin 75mg or Capsule Pregabalin 150 mg.Timepoint: Postoperative pain by VAS score (visual analogue score) at 0,1, 2,4,8,12,24hrs.

Secondary Outcome Measures

Name	Time	Method
Postoperative sedation, nausea vomitting(PONV), dizziness.Timepoint: At Postoperative 1,2,4,8,12,24hrs