Role of the Serial Measurement of Capillary Blood Lactate in the Management of Sepsis Outside the Intensive Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- measurement of capillary blood lactate
研究概览
简要总结
Determination of capillary lactate by using "point-of-care" technique is accessible, fast and allows to quantify the circulatory and metabolic dysfunction caused by sepsis. Compared to conventional assay techniques in arterial blood, capillary assay technique may have an increased susceptibility to metabolic alterations induced by sepsis in its initial stages. This increased sensitivity is not necessarily relevant in the management of the most serious patients for whom the diagnosis is obvious, but it could be very useful in patients for whom a diagnosis of severe sepsis or shock have not yet been adopted, particularly to help better identify patients who would require intensive management and avoid the installation of these serious disorders.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Installation without any plausible explanation of at least one of the following clinical criteria:
- •Chills, fever, mottling, respiratory rate> 20/min; Sat02 < 90% or > 94% with more than 4l O2, heart rate > 90/min,systolic blood pressure < 100 mmHg or 40 mmHg lower compared with normal values, Glasgow coma score <
- •or: .a combination of two (or more) of clinical and laboratory criteria for sepsis.
- •Signed informed consent form
排除标准
- •Need in its current treatment of aerosol administration of beta agonists at a frequency greater than one per 8 hours;
- •Targeted therapeutic measures have already stated for more than 60 minutes;
- •Diagnosis other than Sepsis;
- •Malignant neoplasm or other progressive disease and expected survival was less than 3 months.
结局指标
主要结局
measurement of capillary blood lactate
时间窗: 72 hours after inclusion
次要结局
未报告次要终点