ACTRN12612000375853CompletedNot Applicable
A Single Dose Clinical Trial to Study the Safety, Tolerability, and Pharmacokinetics of Intravenous MK-8226 in Healthy Subjects
Merck Sharp and Dohme Corp, a subsidiary of Merck & Co., Inc.0 sites42 target enrollmentStarted: April 2, 2012Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 42
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomised controlled trial
- Primary Purpose
- Treatment
Eligibility Criteria
- Ages
- 18 Years to 50 Years (—)
- Sex
- All
Inclusion Criteria
- •Subject judged to be in good health based on medical history, physical examination, ECG, vital sign measurements and laboratory safety tests
- •-Non-smoker
- •-BMI <30kg/m2
Exclusion Criteria
- •-Mentally or legally incapacitated or having significant emotional problems or has a history of clinically significant psychiatric disorder
- •-History of any clinically significant diseases/disorders
- •-Creatinine Clearance <80mL/min
- •-History of neoplastic disease
- •-Pregnant, breast feeding or expecting to conceive
- •-Major surgery or blood donation within 4 weeks
- •-Consumes excessive amounts of alcohol or caffeine
- •-History of significant allergies
- •-Regular/recreational drug user
- •-Participated in another clinical study within 4 weeks
- •-Positive to Hepatitis B, C or HIV
- •-Recent history of serious infection/infection requiring systemic antibiotics
- •-Received a live virus vaccine within 4 weeks.
Investigators
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