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Clinical Trials/NCT04187274
NCT04187274
Completed
Not Applicable

Evaluation of the Urethral Photoplethysmography-derived Perfusion Device (IKORUS) in Patients Undergoing Major Abdominal Surgery

Erasme University Hospital1 site in 1 country70 target enrollmentSeptember 4, 2019
ConditionsTechnology

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Technology
Sponsor
Erasme University Hospital
Enrollment
70
Locations
1
Primary Endpoint
Analysis of uPi evolution during surgery and comparison with Stroke volume
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The goal of this observational substudy is to evaluate the feasibility, performance and behavior of the IKORUS (Advanced Perfusion Diagnostics, Villeurbanne, France), a new tissue perfusion device using urethral photoplethysmography in patients undergoing major abdominal surgery and in whom an advanced hemodynamic monitoring is placed.

Detailed Description

Continuous monitoring of tissue perfusion in patients undergoing major surgery remains challenging because of the lack of tools available. Through using urethral photoplethysmography, the urethral perfusion index (uPI) could allow tissue perfusion monitoring through a modified urinary catheter. The goal of this observational study is to evaluate the feasibility , performance and behavior of the IKORUS (Advanced Perfusion Diagnostics, Villeurbanne, France), a new device in the field. We aimed to assess its performance (duration and signal quality), the uPI variations during hemodynamic events (fluid challenge) in patients undergoing major abdominal surgery and equipped with an advanced hemodynamic monitoring.

Registry
clinicaltrials.gov
Start Date
September 4, 2019
End Date
July 30, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Erasme University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Alexandre Joosten, MD PhD

Principal Investigator

Erasme University Hospital

Eligibility Criteria

Inclusion Criteria

  • All adult patients undergoing major abdominal surgeries and equipped with an advanced hemodynamic monitoring for goal directed therapy

Exclusion Criteria

  • Atrial fibrillation
  • Ejection fraction \< 30%

Outcomes

Primary Outcomes

Analysis of uPi evolution during surgery and comparison with Stroke volume

Time Frame: during surgery

Percentage of case time with positive correlation between both variables (positive or negative) during a fluid challenge and during the whole case

Secondary Outcomes

  • Occurrence of decreased perfusion during surgery(during surgery)

Study Sites (1)

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