Comparing the effect of nigella sativa powder and cuminum cyminum powder on eradication of helicobacter pylori, dyspepsia and quality of life in patients with this infectio

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 90

Inclusion Criteria

People who have any of the following conditions can participate in the study:
1.Having positive result of helicobacter pylori infection and dyspepsia symptoms
2.Having positive result of helicobacter pylori infection and dyspepsia symptoms with mild to moderate peptic ulcer
3.Having positive result of helicobacter pylori infection and dyspepsia symptoms with mild to moderate gastritis

Exclusion criteria:
1.Having a history of gastric cancer or gastric surgery
2.Active GI bleeding and intense gastritis
3.Having an inflammatory or chronic disease (kidney disease, liver disease, inflammatory bowel disease, heart ischemia, diabetes, lung disease, asthma, cancer, HIV, systemic inflammation and…)
4.Taking any antibiotics or bismuth from 6 weeks before the study
5.Taking all types of medication for helicobacter pylori before the study
6.Pregnancy or lactation at the same time as studying
7.Drinking alcohol or using narcotic at the same time as studying
8.Eating a specific diet (vegetarian diet and …) at the same time as studying
9.Body mass index greater than 30
10.Exiting patient during the study
11.Any changes in the use of anti-inflammatory drugs and corticosteroids at the same time as studying
12.Any changes in the use of supplements such as omega 3, selenium, zinc, beta carotene, vitamin E, C and… at the same time as studying
13.Unwillingness to continue the study

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HsCRP. Timepoint: at the beginning and the end of the study ( after 8 weeks ). Method of measurement: hsCRP kit.

Secondary Outcome Measures

Name	Time	Method
Eradication percentage of helicobacter pylori. Timepoint: at the end of the study. Method of measurement: stool antigen test of helicobacter pylori.;Malondialdehyde. Timepoint: at the beginning and the end of the study. Method of measurement: malondialdehyde kit.;Interleukin 8. Timepoint: at the beginning and the end of the study. Method of measurement: interleukin 8 kit.;Quality of life. Timepoint: at the beginning and the end of the study. Method of measurement: sf-36 questionnaire.;Dyspepsia symptoms. Timepoint: at the beginning and the end of the study. Method of measurement: ROMEIII questionnaire.