Epidemiology of Young Lung Cancer - Survey

Recruiting

• Conditions: NSCLC
• Interventions: Other: Online Survey

• Registration Number: NCT04640259
• Lead Sponsor: Addario Lung Cancer Medical Institute

Brief Summary

This is a 100% virtual (remote), case-case study to explore potential environmental, lifestyle and genetic factors that may be associated with driver mutations of young lung cancer in the U.S.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-11-18
• Study First Submitted QC: 2020-11-18
• Study First Posted: 2020-11-23
• Study Start: 2021-02-01
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-07
• Last Update Posted: 2025-04-08
• Primary Completion: 2026-12-30
• Study Completion: 2026-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

1. Male or female aged 18 years and over; or the age of majority for their residential state at the time of enrollment
2. Documentation of primary NSCLC, any stage
3. Less than 50 years of age at the time of NSCLC diagnosis
4. Documentation of testing by a CLIA certified lab for genomic drivers of lung cancer
5. Willingness to undergo all study procedure
6. Provision of written informed consent

Exclusion Criteria

1. Male or female aged less than 18 years; or less than the age of majority for their residential state
2. Greater than or equal to 50 years of age at the time of NSCLC diagnosis
3. No documentation of mutation testing
4. Unwilling to undergo all study procedures
5. Unable or unwilling to provide consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
EGFR	Online Survey	-
KRAS	Online Survey	-
NSCLC Other	Online Survey	-
ROS1	Online Survey	-
ALK	Online Survey	-

Primary Outcome Measures

Name	Time	Method
Exploratory epidemiology correlates	1 month	Exploratory correlations between all questionnaire variables (demographic factors, medical history, smoking history, early life exposures (child and mother), residential history, occupational history, menstrual and reproductive history, diet, and physical activity.

Trial Locations

Locations (2)

USC Keck School of Medicine; 🇺🇸 Los Angeles, California, United States

Addario Lung Cancer Medical Institute; 🇺🇸 San Carlos, California, United States