nderstanding the impact of maternal diseases in pregnancy

Not Applicable

• Conditions: Cardiac disease; Kidney disease; Pregnancy; Cardiovascular - Other cardiovascular diseases; Renal and Urogenital - Kidney disease; Reproductive Health and Childbirth - Normal pregnancy

• Registration Number: ACTRN12621001595808
• Lead Sponsor: Margaret Arstall

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-22
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 1300

Inclusion Criteria

1)Are pregnant AND
2)Present with at least one of the following:
a.Congenital cardiac disease
b.Valvular heart disease
c.Cardiomyopathy
d.Ischaemic heart disease
e.Arrhythmia
f.Pulmonary hypertension
g.Aortic pathology
h.Pre-conception diagnosis of CKD of any stage (including dialysis and transplant recipients)
i.Newly identified kidney impairment in pregnancy, defined by any one of the following:
-Two or more serum creatinine readings above the normal local laboratory reference range for pregnancy
-Significant proteinuria during pregnancy (urine PCR> 30 mg/L), not in the context of pre-eclampsia
j.Strong clinical suspicion of underlying CKD in women with acute kidney injury or other comorbidity

Exclusion Criteria

•Physiological palpitations of pregnancy
•Sinus tachycardia without evidence of other cardiac disease
•Pre-eclampsia with proteinuria, but no other features or clinical suspicion of underlying kidney disease or kidney impairment
•Uncomplicated hypertension with no other features of kidney disease

Study & Design

• Study Type: Observational
• Study Design: Not specified