Assessment of Er:YAG Laser-Assisted Surgical Treatment in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical Trial

Not Applicable

Completed

• Conditions: Medication-Related Osteonecrosis of Jaw

• Registration Number: NCT07029815
• Lead Sponsor: Wroclaw Medical University

Brief Summary

The aim of this study is assessing the effectiveness of the Er:YAG laser in relation to the use of conventional surgery in the treatment of drug-induced osteonecrosis of the jaws (MRONJ). The study compares two main treatments for advanced cases of MRONJ or cases that do not show improvement despite conservative or non-surgical treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-01
• Primary Completion: 2023-08-01
• Status Verified: 2025-05
• Study Completion: 2025-05-01
• Study First Submitted: 2025-06-02
• Study First Submitted QC: 2025-06-11
• Last Update Submitted: 2025-06-11
• Study First Posted: 2025-06-19
• Last Update Posted: 2025-06-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• confirmed diagnosis of MRONJ

Exclusion Criteria

• head and neck radiotherapy
• cases requiring hospital admission due to poor general condition

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Complications	Up to 6 months	Occurrence or absence of complications

Trial Locations

Locations (1)

Wroclaw Medical University; 🇵🇱 Wrocław, Poland