Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips

Phase 4

Completed

• Conditions: Alveolar Bone Resorption

• Registration Number: NCT04324697
• Lead Sponsor: October 6 University

Brief Summary

The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone. Without need to use autogenous bone graft techniques that are characterized by more aggressive surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-08
• Primary Completion: 2019-07-01
• Study Completion: 2019-09-05
• Study First Submitted: 2020-03-23
• Study First Submitted QC: 2020-03-25
• Study First Posted: 2020-03-27
• Status Verified: 2020-04
• Last Update Submitted: 2020-06-06
• Last Update Posted: 2020-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Patients with class IV of Cawood and Howell classification in the anterior maxilla.
• Males and females 18-50 years of age.
• Patients with adequate oral hygiene.
• Patients with healed sites for at least 6 months after tooth extraction.
• Patients with an inter-arch distance of at least 6 mm.
• Compliance with all requirements in the study and signing the informed consent.

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Exclusion Criteria

• Patients with diseases of the immune system or systemic disease affecting bone healing
• Patients who are chronic users of medications known to affect the periodontal status.
• Patients with history of intravenous and/or oral bisphosphonate use.
• Pathologic lesions or acute infection in the area of defect.
• Patients who are pregnant or lactating mothers.
• Heavy smokers who smoke more than 10 cigarettes a day.
• Patients with poor oral hygiene that are not amenable to motivation and improvement.
• Patients with history of irradiation of the head and neck region.
• Vulnerable patients.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Alveolar Bone quantity	6 months	Alveolar bone width by millimeters using Cone Beam Computed Tomography

Secondary Outcome Measures

Name	Time	Method
Alveolar Bone quality	7 months	Histological evaluation of status of regenerated bone vitality and remodeling

Trial Locations

Locations (1)

Faculty of Dentistry Ain Shams University; 🇪🇬 Cairo, Egypt