Prostate Diffusion Imaging With Distortion Correction
- Conditions
- Prostate Cancer
- Interventions
- Diagnostic Test: MRI scan
- Registration Number
- NCT06185478
- Brief Summary
There has been literature demonstrating the effectiveness of correcting these MRI images by using an additional measurement of the magnetic field, but the implied improvement in lesion detection in these common distorted regions in the prostate has yet to be shown.
We propose that introducing this distortion correction would greatly improve the DWI images used for tumour detection. For this study we propose testing this hypothesis as a primary objective, and as a secondary objective including additional b-values to further refine the ADC value. The study involves adding one additional distortion correcting scan to the standard clinical study, adding approximately 2 minutes to the study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- SUSPENDED
- Sex
- Male
- Target Recruitment
- 70
- Male
- Aged 18 and over
- No contraindication to MR scanning
- Smokers and non-smokers
- Patients who have had a complete scan on the 3T scan MRI at Norfolk and Norwich University Hospital and have gone on to have a biopsy at the Norfolk and Norwich University Hospital
- Previous diagnosis of prostate cancer, prostatic biopsy or treatment for prostate cancer
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Imaging MRI scan -
- Primary Outcome Measures
Name Time Method MRI image quality 12 months To determine whether correcting for the distortion in MRI images caused by rectal gas improves the image quality and thus diagnostic ability in localising and detecting prostate cancer
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Norfolk and Norwich University Hospitals NHS Foundation Trust
🇬🇧Norwich, Norfolk, United Kingdom