CTRI/2025/07/092001Not Applicable3 期
Effectiveness of Intra-articular Injection with Strengthening Exercise versus Conventional Physiotherapy in Knee Osteoarthritis Patients
Dr Ehsanur Rahman Department of Physiotherapy and Rehabilitation1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月10日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- Not Applicable
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pain by Numeric Pain Rating Scale
研究概览
简要总结
This randomized controlled trial compares the effectiveness of intra-articular corticosteroid injection plus strengthening exercise versus conventional physiotherapy in knee osteoarthritis patients aged 40–70 years. The intervention lasts 8 weeks, with injections given based on pain levels. Primary outcome is pain measured by NPRS, and secondary outcomes include WOMAC, TUG test, goniometer, 30 second Sit-to-Stand test. Follow-up will be done at 6 months to assess long-term effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •The inclusion criteria considered patients aged 40-70 years with knee osteoarthritis confirmed by a rheumatologist (grades I-III in the Kellgren-Lawrence score) who had pain, morning stiffness of shorter than 30 minutes, or knee crepitus.
排除标准
- •Contraindication for IA injection such as overlying skin and soft tissue infection, uncontrolled bleeding diathesis, IA glucocorticoid injection in the past 3 months, patients with secondary OA due to inflammatory arthritis, trauma or infection or history of knee replacement in the same joint and planning for knee surgery within 3 months.
结局指标
主要结局
Pain by Numeric Pain Rating Scale
时间窗: 8 weeks intervention, a follow up will be conducted after 6 months
次要结局
- Physical function by Western Ontario and MacMaster Universities Osteoarthritis Index, Range of motion by Standard Goniometer, Lower limb muscle strength by 30 second Sit-to-Stand Test, Functional mobility by Timed Up and Go test(8 weeks intervention, a follow up will be conducted after 6 months)
研究者
Sunjana Saima Anesha
Jashore University of Science and Technology
研究点 (1)
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