Comparing improvement efficacy of leishmaniasis patients with three treatment methods including combined cryotherapy and interalesional meglumine antimoniate (Glucantime) vs. cryotherapy and interalesional glucantime alone for the treatment of cutaneous leishmaniasis
Phase 2
- Conditions
- Cutaneous Leishmaniasis.Cutaneous Leishmaniasis
- Registration Number
- IRCT138903063862N4
- Lead Sponsor
- Research Council of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
presence of cutaneous leishmaniasis less than 6 months that their disease has been approved by direct smear and stained with Giemsa or positive skin biopsy, a 3-month treatment free interval from the last treatment course. Exclusion criteria: pregnancy, lactating, receiving simultaneously any therapy during study period that has antileishmaniasis effect during 2 months ago, history of significant renal, pulmonary and cardiovascular disease.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete healing. Timepoint: For the first time 6th and 8th weeks after treatment and for the second time in follow up visit after 3 months of beginning the study. Method of measurement: Measuring the size of induration and ulcer.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: at each follow up visit. Method of measurement: Physical exam.