Treatment of Carpal Tunnel in Rheumatoid Arthritis
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- pain intensity
研究概览
简要总结
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy in Rheumatoid arthritis patients proved by nerve conduction studies and ultrasound parameters, this study aims to evaluate the effect of hydro-dissection using insulin versus hyalase versus saline, ultrasounic guided as an effective treatment
详细描述
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy in Rheumatoid arthritis patients proved by nerve conduction studies and ultrasound parameters, this study aims to evaluate the effect of hydro-dissection of median nerve inside CT twice injections with interval 2 weeks using insulin and 10 cc saline versus hyalase and 10 cc saline versus 10 cc saline, ultrasounic guided as an effective treatment of CT
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Rheumatoid arthritis in remission
排除标准
- •active Rheumatoid arthritis
研究组 & 干预措施
Hyalase
injection and hydro-dissection of median nerve using hyaluronidase followed by 10 cc normal saline ultrasonic guided
干预措施: Hylase (Drug)
Placebo
injection and hydro-dissection of median nerve hydro-dissection using 10 cc saline injection ultrasonic guided
干预措施: saline (Other)
Insilin
injection and hydro-dissection of median nerve hydro-dissection using 10 IU insuline followed by 10 cc normal saline ultrasonic guided
干预措施: Insulin (Drug)
结局指标
主要结局
pain intensity
时间窗: 6 months
Visual analog scale 0-100
次要结局
- ultrasound(6 months)
- nerve conduction(6 months)
研究者
Manal Hassanien
principle investigaror
Assiut University