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Clinical Trials/NCT05504018
NCT05504018
Completed
Not Applicable

Clinical and Radiological Evaluation of Anterior Cruciate Ligament Reconstruction Surgery With Follow-up at Least 1 Year

Samsun University1 site in 1 country60 target enrollmentSeptember 2, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anterior Cruciate Ligament Injuries
Sponsor
Samsun University
Enrollment
60
Locations
1
Primary Endpoint
Magnetic Resonance Imaging (MRI) of Graft
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). The patients will be monitored and evaluated preoperatively and also at 6 months and 1 years after the intervention through a clinical visit. Such assessments will include the patient reported outcomes, the objective examination of the knee during a medical examination to quantify its stability and the radiological examination.

Detailed Description

The literature presents a number of studies on the reconstruction of the anterior cruciate ligament, as well as numerous registers, but the identification of factors and parameters determining the outcomes remains largely debated. The study aims to analyze the potentially individual and operative parameters and identify the factors responsible for the clinical and radiological outcomes. In addition to collecting patient data in terms of features and clinical-radiological status, objective data will be documented and correlated. The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). These patients will be followed and evaluated preoperatively, at 6 months and at 1 years after surgery during a clinical visit. Such assessments will include the patient reported outcomes, the objective examination of the knee during a medical examination to quantify its stability and the radiological examination.

Registry
clinicaltrials.gov
Start Date
September 2, 2022
End Date
April 15, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Samsun University
Responsible Party
Principal Investigator
Principal Investigator

Ahmet Emin Okutan

Specialist in Orthopaedics

Samsun University

Eligibility Criteria

Inclusion Criteria

  • Patients who have provided informed written written consent;
  • Patients aged between 18 and 45;;
  • Patients undergoing reconstructive surgical treatment of the anterior cruciate ligament (ACL)

Exclusion Criteria

  • Patients who have not signed informed consent;
  • Patients undergoing any additional concomitant ligament repair or reconstruction at the same surgery
  • Revision procedures
  • Patients unable to lay still in an MRI or CT scanner
  • Patients with a torn ACL or previous ACL reconstruction in the contralateral knee.

Outcomes

Primary Outcomes

Magnetic Resonance Imaging (MRI) of Graft

Time Frame: 1 year

Graft maturation on MRI using T2 Turbo Spin Echo (TSE) sequence without fat saturation

Secondary Outcomes

  • Isokinetic Dynamometer(1 year)
  • Marx Activity Rating Score(1 year)
  • Difference in Computed Tomography (CT) imaging of Tunnels(1 day, 6 months, 1 year)
  • International Knee Documentation Committee (IKDC)(1 year)

Study Sites (1)

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