Comparitive clinical study on efficacy of bhallatakadya churna and somraji tail with psora capsule and psora oil in the management of ekkushtha with reference to psoriasis

INTRODUCTION

Skin is the largest organ in the body and barrier between body’s internal as well as external environment. In ayurveda skin is one among five gyanendriya’s responsible for ‘sparsh gyan’ and skin disease are collectively considered under a common term ‘kushtha’ where ekkushtha is one under it which finds similarity with psoriasis.

Psoriasis is a chronic systemic autoimmune skin disorder characterized by well defined erythematosus plaques covered by silvery flaky scales mainly affecting skin and joints. Its prevalence in  World is 2-3% of total population and in India it is about 0.44-2.8%. Males are being affected by psoriasis more than female.

The exact etiology of psoriasis is still not established but certain diets, environmental factors ,genetic factors and immunological factors are considered the cause of it. In ayurveda it is mentioned that aharaj nidan like taking excessive amount of newly formed rice, heavily digestible food , citrus fruits, curd, fish, unrefined sesame oil and viharaj nidan like sleeping at day time, supressing the natural urges of body, excessive exposure to sunrays, excessive worry, grief are the causative factors. Other factors such as seasonal changes, alcohol, hypocalcemia and some infections can also trigger psoriasis.

The common sites of occurrence of psoriasis are scalp, elbow, knee, earlobes and sole which are also considered as the location of kapha and vata. The derangement of seven factors involving tridoshas (vata, pitta, kapha) along with twak (skin), rakta (blood tissues),  mamsa  (muscle tissues) and lasika (blood plasma) are the basis of vitiation of srotas . These vitiated factors enter into gambhir dhatus(deeper body tissue element) and srotas (body channels) producing scaly lesion and other symptoms.

BASIS OF MEDICINE SELECTION

1.     Bhallatakadya churna is classic ayurvedic formulation mentioned in kushtha chapter of shloka no. 302,303,304 of gad nigraha having contents which collectively works as rakta shodhak and prasadak , has immune modulation, and anti stress properties along with vatakapha shamak effect which would help in breaking the pathology of ekkushtha.

2.     Bakuchi and bhallatak present in the drug has kushthaghna properties that directly act on skin disorders especially chronic ones.

3.     Bakuchi is present in bhallatakadya churna as well as somraji tail which has properties like raktashodhak, (blood purifying effect), lekhan (helps in removing dead skin), and varnya(improves complexion of skin)

4.     Bramhi and Shankhpushpi has anti stress properties which will reduce the stress of the patient.

5.     Haldi and Daruhaldi present in the Somraji Tail has  anti inflammatory ,kandughna, and rakta shodhak properties.

 NEED OF STUDY

1.     To fill the gap in current state of ayurveda research so as to identify trigger factors, relapsing and recurring condition of psoriasis.

2.     The chronic nature, recurring pattern and visibility of psoriasis produces a huge adverse impact on the psychological and social aspect of patient life.

3.     Psychological disability affects the daily routine as well as social interaction.

4.     In present era, skin disorders are commonly found in day to day practice and according to roxburgh’s common skin disease book approx 10-15% of the patients suffering from psoriasis do not respond to available therapies. Therefore a complete successful treatment method along with dietary changes to reduce its reccurence is needed which would be highly effective.

5.     Psoriasis affects quality of life , ayurvedic studies can help develop community level guidelines for prevention, awareness, and early intertvention.

6.     Psoriasis involves both skin and systemic issues like inflammation,stress,immunity and ayurveda provides a mind body approach through diet (ahara), lifestyle (vihara) and mental wellness practices (satvavjay chikitsa)

BASIS OF MEDICINE SELECTION

1.     Bhallatakadya churna is classic ayurvedic formulation mentioned in kushtha chapter of shloka no. 302,303,304 of gad nigraha having contents which collectively works as rakta shodhak and prasadak , has immune modulation, and anti stress properties along with vatakapha shamak effect which would help in breaking the pathology of ekkushtha.

2.     Bakuchi and bhallatak present in the drug has kushthaghna properties that directly act on skin disorders especially chronic ones.

3.     Bakuchi is present in bhallatakadya churna as well as somraji tail which has properties like raktashodhak, (blood purifying effect), lekhan (helps in removing dead skin), and varnya(improves complexion of skin)

4.     Bramhi and Shankhpushpi has anti stress properties which will reduce the stress of the patient.

5.     Haldi and Daruhaldi present in the Somraji Tail has  anti inflammatory ,kandughna, and rakta shodhak properties.

 NEED OF STUDY

1.     To fill the gap in current state of ayurveda research so as to identify trigger factors, relapsing and recurring condition of psoriasis.

2.     The chronic nature, recurring pattern and visibility of psoriasis produces a huge adverse impact on the psychological and social aspect of patient life.

3.     Psychological disability affects the daily routine as well as social interaction.

4.     In present era, skin disorders are commonly found in day to day practice and according to roxburgh’s common skin disease book approx 10-15% of the patients suffering from psoriasis do not respond to available therapies. Therefore a complete successful treatment method along with dietary changes to reduce its reccurence is needed which would be highly effective.

5.     Psoriasis affects quality of life , ayurvedic studies can help develop community level guidelines for prevention, awareness, and early intertvention.

6.     Psoriasis involves both skin and systemic issues like inflammation,stress,immunity and ayurveda provides a mind body approach through diet (ahara), lifestyle (vihara) and mental wellness practices (satvavjay chikitsa)

In this study two groups are taken , having sample size of 40 and each group has 20 participants . In 1st group Bhallatakadya Churna and Somraji Tail will be given and in 2nd group Psora Capsule and Psora Oil (from Ayulabs pharmaceuticals )will be given.

ANTICIPATED OUTCOME-

1.     Bhallatakadya Churna and Somraji tail will prevent the recurrence of ekkustha.

2.     Bhallatakadya Churna will manage the stress level of the patient very well as it has drugs like brahmi, shankhpushpi having anti stress properties in its composition.