Examining the role of context for the subjective perception of alcohol-related stimuli by recording eye movements in volunteers with regular alcohol consumptio
- Conditions
- F10Mental and behavioural disorders due to use of alcohol
- Registration Number
- DRKS00019822
- Lead Sponsor
- Zentralinstitut für Seelische Gesundheit Mannheim
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
• Men and women between 18 and 65 years
• Diagnosis: no axis I or axis II disorder, except nicotine dependence (F17.2)
• Meeting the criteria for social drinking: on average at least 2 alcoholic drinks (12g alcohol per drink) per week, within the last year [31, 32]
• Sufficient ability to communicate with the investigators, to answer questions in oral and written form
• Ability to agree after detailed written consent (Fully Informed Consent)
• informed consent must be available in written form (Written Informed Consent)
• Normal or correctable (with contact lenses) poor eyesight
• Withdrawal of the declaration of consent
• Average alcohol consumption <2 alcoholic beverages (12 g alcohol per drink) per week, within the last year [38,39]
• Alcohol intoxication (breath alcohol concentration> 0.3 ‰)
• Axis I disorder according to DSM 5 or ICD-10 (except for nicotine dependence or nicotine abuse within the last 12 months)
• Pharmacotherapy with psychoactive substances within the last 14 days
• Current substance abuse (THC, amphetamine, opiates, benzodiazepines, barbiturates and cocaine)
• Insufficient ability to communicate with the examiner
• wearing glasses (without the possibility to wear contact lenses)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim is to investigate the effect of different contexts on the subjective perception of alcohol-related and neutral images, as well as the emergence of attention distortion towards alcohol-related images within a group of social drinkers (within-subject design). Out of that a better understanding of the basis of these reactions should be captivate in order to work out which contexts can enhance drinking behavior.
- Secondary Outcome Measures
Name Time Method It is expected that the relationships between the subjective perception of alcohol-associated and neutral image stimuli with objective measures of eye movement (fixation, pupil size, saccades) to specific stimulus characteristics (spatial context, social aspect) and the time course of attention directed to these stimuli can be better characterized. By identifying the mechanisms that have a specific influence on the emergence of attention-focussing and alcohol craving in social drinkers, in the future an improved care of patients (e.g. by improving existing cue-exposure methods with optimized imagery) and, in the long run, a reduction of the relapse probatility are possible.