the Evaluation of the Efficacy of TCI66207 on the Skin.

Not Applicable

Completed

• Conditions: Skin Diseases
• Interventions: Dietary Supplement: Placebo Essence; Dietary Supplement: TCI66207 Essence

• Registration Number: NCT05143034
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

The purpose of this study is to explore the evaluation of the efficacy of TCI66207 deep-sea live-face bacteria on the skin.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-01
• Primary Completion: 2019-11-30
• Study Completion: 2019-12-31
• Status Verified: 2021-11
• Study First Submitted: 2021-11-22
• Study First Submitted QC: 2021-11-22
• Study First Posted: 2021-12-03
• Last Update Submitted: 2021-12-06
• Last Update Posted: 2021-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Healthy volunteers aged above 20 years old
2. Subject has dull skin.

Exclusion Criteria

1. .Subject with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
2. Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
3. Female who is pregnant or nursing or planning to become pregnant during the course of the study.
4. Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
5. Subjects who have large spots (area >3 square centimeter) or abnormal acne.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo Essence	Placebo Essence	-
TCI66207 Essence	TCI66207 Essence	Essence

Primary Outcome Measures

Name	Time	Method
The change of skin moisture	Subjects will be tested in the 4th week.	Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin elasticity	Subjects will be tested in the 4th week.	Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curvesCorneometer® units 0-120
The change of skin wrinkles	Subjects will be tested in the 4th week.	VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units
The change of skin collagen density	Subjects will be tested in the 4th week.	DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score
The change of skin texture	Subjects will be tested in the 4th week.	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin pores	Subjects will be tested in the 4th week.	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

Trial Locations

Locations (1)

Research & Design Center, TCI CO., Ltd; 🇨🇳 Taipei, Neipu Township, Taiwan