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临床试验/NCT06763562
NCT06763562招募中不适用

The Impact of Different Food Orders on Blood Glucose and Fuel Use At Rest

Old Dominion University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年1月5日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
60
试验地点
1
主要终点
Respiratory exchange ratio

研究概览

简要总结

Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls. However, gaps remain in the literature in this area of research, and currently little is known about how substrate (fuel) use is impacted by altering food order. In addition, most studies to date have used a mix of meat and plant foods, while little research has focused exclusively on vegetarian foods. This randomized experiment will examine how altering the order of foods eaten in a vegetarian meal impacts blood glucose and fuel utilization at rest.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •18-70 years old
  • •Free from any allergy or condition that precluding consumption of edamame, butter, and rice
  • •Not currently pregnant
  • •Free of any medical conditions requiring the use of insulin
  • •Have no history of bariatric surgery
  • •Have no implanted electrical devices such as a pacemaker

排除标准

  • •Younger than 18 and older than 70 years old
  • •Having an allergy or condition that precludes consumption of edamame, butter, and rice
  • •Currently pregnant
  • •Any medical conditions requiring the use of insulin
  • •A history of bariatric surgery
  • •Having an implanted electrical device such as a pacemaker

研究组 & 干预措施

Carbohydrate-first meal

Experimental

干预措施: Carbohydrate-first meal (Other)

Carbohydrate-last meal

Experimental

干预措施: Carbohydrate-last meal (Other)

结局指标

主要结局

Respiratory exchange ratio

时间窗: 90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal)

Ratio of carbon dioxide production and oxygen consumption for determination of fuel use

次要结局

  • Fat use(90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal))
  • Carbohydrate use(90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal))
  • Blood glucose(90 minutes (baseline/premeal and 30, 60, and 90 minutes postmeal))
  • Hunger-satiety perceptions(90 minutes (baseline/premeal and 30, 60, and 90 minutes postmeal))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Patrick Wilson, PhD

Associate Professor of Exercise Science

Old Dominion University

研究点 (1)

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