Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis

Completed

• Conditions: Diverticulosis, Colonic; Abdominal Adhesion; Diverticulitis

• Registration Number: NCT05384925
• Lead Sponsor: Assaf-Harofeh Medical Center

Brief Summary

Background \& Aims:

Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased intraluminal colonic pressure. We assessed whether previous abdominal surgery is associated with colonic diverticulosis or diverticulitis.

Methods:

The investigators analyzed data from a prospective study of patients undergoing colonoscopy for different indications from 2020 through 2021. Patients completed a structured questionnaire concerning previous abdominal surgeries, dietary and lifestyle exposures including smoking and alcohol use, and co-morbidities.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-12
• Primary Completion: 2021-05-22
• Study Completion: 2022-04-01
• Status Verified: 2022-05
• Study First Submitted: 2022-05-12
• Study First Submitted QC: 2022-05-17
• Study First Posted: 2022-05-20
• Last Update Submitted: 2022-05-22
• Last Update Posted: 2022-05-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 359

Inclusion Criteria

• patients > 18 years old who are going through colonoscopy in shamir medical center for any reason

Exclusion Criteria

• inadequate preparation (Boston Bowel Preparation Quality Scale <6);
• previous colonic resection based on history and colonoscopy;
• previous colon cancer.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
correlation between prior abdominal surgery and the development of diverticulosis	in the end of the study (estimated in 1 year)	the investigators are willing to see if prior abdominal surgery raise the patient's risk of developing future diverticulosis. The investigators use questionere to collect data from patients. The final measurements will be calculatrd with spss software

Trial Locations

Locations (1)

Asag Harofeh Medical Center; 🇮🇱 Be'er Ya'aqov, Israel