NCT00721474已完成1 期
An Open-Label, Randomized, Single-Dose, 2-Period Crossover Study to Determine the Effect of a High-Fat Meal on the Relative Bioavailability and Pharmacokinetics of a Single Dose of Bosutinib Administered Orally to Healthy Subjects
Wyeth is now a wholly owned subsidiary of Pfizer0 个研究点目标入组 24 人开始时间: 2008年9月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 主要终点
- Pharmacokinetics (plasma concentrations)
研究概览
简要总结
A Study to determine if a high-fat meal has an effect on the pharmacokinetics of bosutinib.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men, age 18-50;
- •Healthy women of nonchildbearing potential, age 18-50.
排除标准
- 未提供
研究组 & 干预措施
2
Experimental
Bosutinib fed
干预措施: Bosutinib (Drug)
1
Experimental
Bosutinib fasting
干预措施: Bosutinib (Drug)
结局指标
主要结局
Pharmacokinetics (plasma concentrations)
时间窗: 4 weeks
次要结局
未报告次要终点
研究者
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