Effects of norepinephrine versus phenylephrine bolus prophylaxis for blood pressure drop after spinal anesthesia for surgery in elderly patients: a randomized double-blind study.
Not Applicable
- Conditions
- Health Condition 1: N400- Benign prostatic hyperplasia without lower urinary tract symptomsHealth Condition 2: M169- Osteoarthritis of hip, unspecifiedHealth Condition 3: M179- Osteoarthritis of knee, unspecified
- Registration Number
- CTRI/2024/02/063094
- Lead Sponsor
- All India Institute of Medical Sciences Sijua Patrapada Bhubaneswar, Odisha India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I/II patients of age = 60 years undergoing surgery using spinal anesthesia.
Exclusion Criteria
Patients with known cardiac abnormalities,
Use of Mono Amine Oxidase inhibitor,
Patients with known allergy to the study drugs,
Patients with contraindications for SAB,
Patient refusal for consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of bolus norepinephrine vs phenylephrine on the incidence of bradycardia in elderly patients under spinal anesthesia.Timepoint: first 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method 1.To compare the number of episodes of hypotension and the time of the first episode of hypotension <br/ ><br>2.To compare the intraoperative use of norepinephrine, phenylephrine, ephedrine, atropine and fluids <br/ ><br>3.To compare the changes in the Flow time corrected (FTc) (preoperative, 5min after spinal anesthesia, and immediately after surgery in PACU) <br/ ><br>4.To compare the episodes of reactive hypertension and postoperative complications within first 24hrs. <br/ ><br>Timepoint: first 24 hours postoperatively