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Evaluation the effect of Pentoxifylline on spermatozoa of Azoospermic patients

Phase 4
Conditions
azoospermia.
Male infertility
Registration Number
IRCT20200705048020N1
Lead Sponsor
Yazd University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Male
Target Recruitment
40
Inclusion Criteria

All non obstructive azoospermia patients less than 50 years old and more than 50 number sperm
women less than 40 years old without any Infertility problems

Exclusion Criteria

HIV- positive patient with any pathology
Patients with very low sperm count
women more than 40 years old
Couples who also have problems with female infertility

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Fertilization rate. Timepoint: One day after assisted artificial insemination. Method of measurement: formation of 2 pronucleous.;Embryo formation rate. Timepoint: 3 days after assisting artificial insemination. Method of measurement: 8 cell embryo formation.;Embryo morphokinetic rate. Timepoint: From the time of pronucleous formation until the time of embryo transfer to the mother's uterus. Method of measurement: Time Lapse Incubator.;Chemical pregnancy rate. Timepoint: One week after the embryo transfer to the uterus. Method of measurement: Blood ßHCG Measurement.
Secondary Outcome Measures
NameTimeMethod
Clinical pregnancy rate. Timepoint: 7 weeks after embryo transfer to the uterus. Method of measurement: Assessment of cardiovascular formation using ultrasound examination.
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