Oxytocin's Effect on Social Pain Empathy
- Registration Number
- NCT03122067
- Lead Sponsor
- University of Electronic Science and Technology of China
- Brief Summary
The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy
- Detailed Description
In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 60
Inclusion Criteria
- healthy participants without past or current psychiatric or neurological disorders
Exclusion Criteria
- history of head injury
- medical or psychiatric illness
- smoking or drinking 24 hours before experiment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description oxytocin group oxytocin treatment male participants with oxytocin treatment placebo group placebo treatment male participants with placebo treatment
- Primary Outcome Measures
Name Time Method Neural activity changes associated with oxytocin administration 45-60 minutes after drug administration fMRI-assessed brain activity during observing other being socially excluded
- Secondary Outcome Measures
Name Time Method Behavioral changes associated with oxytocin administration: ball-tossing 45-60 minutes after drug administration Number of tosses to the other players (the excluder, new player, or previously excluded player)
Trial Locations
- Locations (1)
School of Life Science and Technology, University of Electronic Science and Technology of China
🇨🇳Chendu, Sichuan, China