MedPath

Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery

Phase 3
Active, not recruiting
Conditions
Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Non-Cutaneous Melanoma
Recurrent Cutaneous Melanoma
Recurrent Mucosal Melanoma
Clinical Stage III Cutaneous Melanoma AJCC v8
Metastatic Cutaneous Melanoma
Metastatic Mucosal Melanoma
Recurrent Non-Cutaneous Melanoma
Non-Cutaneous Melanoma
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Other: Quality-of-Life Assessment
Registration Number
NCT02506153
Lead Sponsor
National Cancer Institute (NCI)
Brief Summary

This randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant interferon alfa-2B or ipilimumab, in treating patients with stage III-IV melanoma that has been removed by surgery but is likely to come back or spread. High-dose recombinant interferon alfa-2B may help shrink or slow the growth of melanoma. Immunotherapy with monoclonal antibodies, such as ipilimumab and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether pembrolizumab is more effective than the current standard of care in treating patients with melanoma.

Detailed Description

PRIMARY OBJECTIVES:

I. To compare overall survival (OS) of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon recombinant interferon alfa-2b (alfa-2b) or ipilimumab versus MK-3475 (pembrolizumab).

II. Among patients who are PD-L1 positive, to compare OS of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon alfa-2b or ipilimumab versus MK-3475 (pembrolizumab).

III. To compare relapse-free survival (RFS) of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon alfa-2b or ipilimumab to MK-3475 (pembrolizumab).

SECONDARY OBJECTIVES:

I. To estimate OS and RFS for patients who are PD-L1 negative or PD-L1 indeterminate in this population.

II. To compare OS and RFS of patients between the two arms within PD-L1 positive and negative subgroups and to look at the interaction between PD-L1 (positive versus negative) and treatment arm.

III. To assess the safety and tolerability of the regimens.

ADDITIONAL OBJECTIVES:

I. To bank tissue and whole blood in anticipation of future correlative studies in this patient population.

II. To evaluate PD-L1 expression through immunohistochemistry assay. III. To evaluate the effect of treatment-related side effects that may have an impact on the health-related domains of quality of life (QOL) using the Functional Assessment of Cancer Therapy (FACT)-Biological Response Modifiers (BRM), European Quality of Life Five Dimension Three Level Scale (EQ-5D-3L), and Functional Assessment of Chronic Illness Therapy Diarrhea (FACIT-D) between patients treated with physician/patient choice of either high-dose interferon alfa-2b or ipilimumab and MK-3475 (pembrolizumab).

IV. Pharmacokinetic (PK) and anti-drug antibody (ADA) testing will be performed on all patients receiving MK-3475 (pembrolizumab).

TRANSLATIONAL OBJECTIVES RELATED TO T-CELL RECEPTOR BETA CHAIN SEQUENCING:

I. To evaluate the association between TCR beta variable gene (TRBV) haplotype and grade 3-4 immune-related adverse events (irAEs) among stage III melanoma patients treated with adjuvant ipilimumab or pembrolizumab.

II. To describe the TRBV haplotype distribution among this cohort of patients studied.

TRANSLATIONAL MEDICINAL OBJECTIVE RELATED TO ASSOCIATION OF CIRCULATING TUMOR DNA (ctDNA) WITH RELAPSE-FREE SURVIVAL IN HIGH-RISK, RESECTED MELANOMA PATIENTS.

I. To evaluate associations between pretreatment ctDNA (present versus absent) and relapse within 2 years of randomization in a case-control analysis across treatment arms.

II. To evaluate associations between pretreatment ctDNA (present versus absent) and relapse within 2 years of randomization in a case-control analysis across treatment arms.

III. To evaluate associations between pretreatment ctDNA and relapse within 2 years of randomization in a case-control analysis within each treatment arm (after treatment arm data are unblinded to investigators).

IV. To evaluate associations between "early-on treatment" ctDNA levels and relapse within 2 years of randomization.

V. To describe ctDNA levels at end of therapy and time of relapse.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I:

INDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity.

MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity.

Patients undergo computed tomography (CT) scan, positron emission tomography (PET) scan, magnetic resonance imaging (MRI) and blood sample collection throughout the study.

After completion of study treatment, patients are followed up at 30 days, 6 and 12 weeks, every 3 months for 2 years, every 6 months for 3 years, and then every 12 months for 5 years.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
1301
Inclusion Criteria
  • STEP 1 REGISTRATION:
  • Patients must have completely resected melanoma of cutaneous origin or of unknown primary in order to be eligible for this study; patients must be classified as stage IIIA (N2a), IIIB, IIIC, or stage IV melanoma; patients with non-ulcerated T1b N1a disease are not eligible; patients with melanoma of mucosal or other non-cutaneous origin are eligible; patients with melanoma of ocular origin are not eligible; patients with a history of brain metastases are ineligible
  • Patients are eligible for this trial either at initial presentation of their melanoma or at the time of the first detected nodal, satellite/in-transit, distant metastases, or recurrent disease in prior lymphadenectomy basin or distant site; nodal, satellite/in-transit metastasis, distant metastases or disease in a prior complete lymphadenectomy basin must have been confirmed histologically by hematoxylin and eosin (H & E) stained slides
  • Patients with multiple regional nodal basin involvement are eligible; gross or microscopic extracapsular nodal extension is permitted
  • Patients at initial presentation of melanoma must undergo an adequate wide excision of the primary lesion, if present; patients with previously diagnosed melanoma must have had all current disease resected with pathologically negative margins and must have no evidence of disease at the primary site or must undergo re-resection of the primary site; a full lymphadenectomy meeting the criteria outlined is required for all node-positive patients including those with positive sentinel nodes; patients with recurrent disease who have had a prior complete lymphadenectomy fulfill this requirement as long as all recurrent disease has been resected; for all patients, all disease must have been resected with negative pathological margins and no clinical, radiologic, or pathological evidence of any incompletely resected melanoma; patients must be registered within 98 days of the last surgery performed to render the patient free of disease
  • Patients must have available and be willing to submit a minimum of five unstained slides from primary, lymph node, or metastatic site to determine PD-L1 expression; the tumor tissue must be adequate for PD-L1 testing (defined as >= 100 tumor cells as confirmed by the treating institution's local pathologist); this must be documented by having a pathologist sign the S1404 Local Pathology Review form prior to step 1 registration; the specimens may come from an archived block but must be submitted within 20 days from cutting the slides
  • Patients must be offered the opportunity to participate in specimen banking as outlined
  • Patients must be willing to have blood draws for PK/ADA analysis as outlined, should the patient be randomized to the MK-3475 arm
  • Patients may have received prior radiation therapy, including after the surgical resection; all adverse events associated with prior surgery and radiation therapy must have resolved to =< grade 1 prior to registration
  • Patients must not have received neoadjuvant treatment for their melanoma; patients must not have had prior immunotherapy including, but not limited to ipilimumab, interferon alfa-2b, high dose IL-2, pegylated (PEG)-IFN, anti-PD-1, anti-PD-L1 intra-tumoral, or vaccine therapies; patients must not be planning to receive any of the prohibited therapies during the screening or treatment phases of the study
  • Patients must not be planning to receive concomitant other biologic therapy, radiation therapy, hormonal therapy, other chemotherapy, surgery or other therapy after step 2 registration
  • All patients must have disease-free status documented by a complete physical examination and imaging studies within 42 days prior to registration; imaging studies must include a total body positron emission tomography (PET)-computed tomography (CT) scan that is of diagnostic quality (with or without brain) or a CT of the chest, abdomen and pelvis; for patients with melanoma arising from the head and neck, dedicated neck imaging (CT with IV contrast or PET-CT through the region) is required; if the patient has had unknown primary with disease in the axilla, neck imaging is required to assure region is clear of cancer; CT imaging should be done with intravenous contrast if there are no contraindications for it; any other clinically-indicated imaging studies if performed (e.g. bone scan) must show no evidence of disease
  • All patients must have a CT or magnetic resonance imaging (MRI) of the brain within 90 days prior to registration; the brain CT or MRI should be performed with intravenous contrast (unless contraindicated)
  • Absolute neutrophil count (ANC) >= 1,500 microliter (mcL) (within 42 days prior to registration)
  • Platelets >= 100,000 mcL (within 42 days prior to registration)
  • Hemoglobin >= 10 g/dL (within 42 days prior to registration)
  • Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except Gilbert's syndrome, who must have a total bilirubin < 3.0 mg/dL) (within 42 days prior to registration)
  • Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) and serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 2 x IULN (within 42 days prior to registration)
  • Alkaline phosphatase =< 2 x IULN (within 42 days prior to registration)
  • Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min (within 42 days prior to registration)
  • Patients must have lactate dehydrogenase (LDH) performed within 42 days prior to registration
  • Patients must have Zubrod performance status =< 1
  • Patients must have a baseline electrocardiogram (ECG) performed within 42 days of registration that is normal or considered not clinically significant by the site investigator
  • Patients must not have a history of (non-infectious) pneumonitis that required steroids or current pneumonitis
  • Patients must not have an active infection requiring systemic therapy
  • Patients must not have active autoimmune disease that has required systemic treatment in past 2 years (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs); replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment
  • Patients must not have received live vaccines within 42 days prior to registration; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, shingles, yellow fever, rabies, bacillus Calmette-Guerin (BCG), and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines, and are not allowed
  • Patients known to be human immunodeficiency virus (HIV) positive are eligible if they meet the following criteria within 30 days prior to registration: stable and adequate cluster of differentiation 4 (CD4) counts (>= 350 mm^3), and serum HIV viral load of < 25,000 IU/ml; patients may be on or off anti-viral therapy so long as they meet the CD4 count criteria
  • Patients must not have known active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection prior to registration
  • Patients must not have a history or current evidence of any condition, therapy or laboratory abnormality that might confound the trial results, interfere with the patient's participation for the full duration of the trial, or indicate that participation in the trial is not in the patient's best interests, in the opinion of the treating investigator
  • No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, lobular carcinoma of the breast in situ, atypical melanocytic hyperplasia or melanoma in situ, adequately treated stage I or II cancer (including multiple primary melanomas) from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for three years
  • Women of childbearing potential must have a negative urine or serum pregnancy test within 28 days prior to registration; women/men of reproductive potential must have agreed to use an effective contraceptive method for the course of the study through 120 days after the last dose of study medication; should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy, or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures, he/she is responsible for beginning contraceptive measures; patients must not be pregnant or nursing due to unknown teratogenic side effects
  • Patients who are able to complete questionnaires in English, Spanish or French must participate in the quality of life assessments; (those patients who cannot complete the quality of life questionnaires in English, Spanish or French can be registered to S1404 without contributing to the quality of life studies)
  • Patients must be informed of the investigational nature of this study and must sign and give written informed consent for this protocol in accordance with institutional and federal guidelines
  • As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
  • STEP 2 REGISTRATION (RANDOMIZATION CRITERIA):
  • Patients must not be registered until receiving confirmation from the Southwest Oncology Group (SWOG) Statistical Center that the patient's tissue specimen was adequate for PD-L1 testing; patients must be registered within 7 working days of receiving the e-mail notification
  • Women of childbearing potential must plan to have a urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication; if the urine test is positive or cannot be confirmed as negative, a negative serum pregnancy test will be required
  • No tests or exams are required to be repeated for step 2 registration (randomization); however, patients who are known to have a change in eligibility status after step 1 registration are not eligible for step 2 registration; for example, ANC is not required to be repeated between step 1 and step 2 registration, but the most recent ANC performed before step 2 registration is required to be >= 1,500 mcL
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Biospecimen CollectionINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Computed TomographyINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)IpilimumabINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Magnetic Resonance ImagingINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Positron Emission TomographyINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Quality-of-Life AssessmentINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)Recombinant Interferon Alfa-2bINDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm II (pembrolizumab)Biospecimen CollectionPatients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm II (pembrolizumab)Magnetic Resonance ImagingPatients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm II (pembrolizumab)PembrolizumabPatients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm II (pembrolizumab)Positron Emission TomographyPatients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Arm II (pembrolizumab)Quality-of-Life AssessmentPatients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Primary Outcome Measures
NameTimeMethod
Overall Survival (OS)5 years after last randomization

Time from date of randomization to date of death due to any cause. Patients known to be alive are censored at date of last contact. The results were presented as 5-year OS estimate.

Secondary Outcome Measures
NameTimeMethod
Relapse-free Survival (RFS)5 years after last randomization

Time from date of randomization to date of first documentation of relapse or death due to any cause. Patients last known to be alive and relapse-free are censored at date of last contact.

Overall Survival (OS) in Participants Who Are PD-L1 Positive94 months; from study start November 10, 2015 to September 15, 2023

Time from date of randomization to date of death due to any cause. Patients known to be alive are censored at date of last contact.

Relapse-free Survival (RFS) in Participants Who Are PD-L1 Positive5 years after last randomization

Time from date of randomization to date of first documentation of relapse or death due to any cause. Patients last known to be alive and relapse-free are censored at date of last contact.

Number of Participants With Gr 3 Through 5 Adverse Events That Are Related to Study DrugsRandomized patients will be followed until death or 94 months (from study start November 10, 2015 to September 15, 2023), whichever occurs first.

Only adverse events that are possibly, probably or definitely related to study drug are reported. CTCAE Version 5.0 was used for all AE reporting.

Trial Locations

Locations (578)

Kaiser Permanente-Irvine

🇺🇸

Irvine, California, United States

University of Alabama at Birmingham Cancer Center

🇺🇸

Birmingham, Alabama, United States

Cancer Center at Saint Joseph's

🇺🇸

Phoenix, Arizona, United States

Virginia G Piper Cancer Care-Del Camino

🇺🇸

Scottsdale, Arizona, United States

Banner University Medical Center - Tucson

🇺🇸

Tucson, Arizona, United States

University of Arizona Cancer Center-North Campus

🇺🇸

Tucson, Arizona, United States

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

Highlands Oncology Group - Rogers

🇺🇸

Rogers, Arkansas, United States

Kaiser Permanente-Anaheim

🇺🇸

Anaheim, California, United States

Sutter Auburn Faith Hospital

🇺🇸

Auburn, California, United States

Kaiser Permanente-Baldwin Park

🇺🇸

Baldwin Park, California, United States

Kaiser Permanente-Bellflower

🇺🇸

Bellflower, California, United States

UC Irvine Health Cancer Center-Newport

🇺🇸

Costa Mesa, California, United States

City of Hope Comprehensive Cancer Center

🇺🇸

Duarte, California, United States

Kaiser Permanente-Fontana

🇺🇸

Fontana, California, United States

Kaiser Permanente-Fremont

🇺🇸

Fremont, California, United States

Palo Alto Medical Foundation-Fremont

🇺🇸

Fremont, California, United States

Kaiser Permanente-Fresno

🇺🇸

Fresno, California, United States

Kaiser Permanente South Bay

🇺🇸

Harbor City, California, United States

UC San Diego Moores Cancer Center

🇺🇸

La Jolla, California, United States

Kaiser Permanente Los Angeles Medical Center

🇺🇸

Los Angeles, California, United States

Los Angeles General Medical Center

🇺🇸

Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center

🇺🇸

Los Angeles, California, United States

Kaiser Permanente West Los Angeles

🇺🇸

Los Angeles, California, United States

Cedars Sinai Medical Center

🇺🇸

Los Angeles, California, United States

UCLA / Jonsson Comprehensive Cancer Center

🇺🇸

Los Angeles, California, United States

Fremont - Rideout Cancer Center

🇺🇸

Marysville, California, United States

Memorial Medical Center

🇺🇸

Modesto, California, United States

Kaiser Permanente-Modesto

🇺🇸

Modesto, California, United States

Palo Alto Medical Foundation-Camino Division

🇺🇸

Mountain View, California, United States

USC Norris Oncology/Hematology-Newport Beach

🇺🇸

Newport Beach, California, United States

Sutter Cancer Research Consortium

🇺🇸

Novato, California, United States

Kaiser Permanente-Oakland

🇺🇸

Oakland, California, United States

Saint Joseph Hospital - Orange

🇺🇸

Orange, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center

🇺🇸

Orange, California, United States

Palo Alto Medical Foundation Health Care

🇺🇸

Palo Alto, California, United States

Stanford Cancer Institute Palo Alto

🇺🇸

Palo Alto, California, United States

Kaiser Permanente - Panorama City

🇺🇸

Panorama City, California, United States

Kaiser Permanente-Redwood City

🇺🇸

Redwood City, California, United States

Kaiser Permanente-San Diego Mission

🇺🇸

San Diego, California, United States

Kaiser Permanente-Richmond

🇺🇸

Richmond, California, United States

Kaiser Permanente-Riverside

🇺🇸

Riverside, California, United States

Kaiser Permanente-Roseville

🇺🇸

Roseville, California, United States

Sutter Roseville Medical Center

🇺🇸

Roseville, California, United States

Sutter Medical Center Sacramento

🇺🇸

Sacramento, California, United States

University of California Davis Comprehensive Cancer Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-South Sacramento

🇺🇸

Sacramento, California, United States

Kaiser Permanente Sacramento Medical Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-San Diego Zion

🇺🇸

San Diego, California, United States

California Pacific Medical Center-Pacific Campus

🇺🇸

San Francisco, California, United States

Kaiser Permanente-San Francisco

🇺🇸

San Francisco, California, United States

Kaiser Permanente-Santa Teresa-San Jose

🇺🇸

San Jose, California, United States

Kaiser Permanente San Leandro

🇺🇸

San Leandro, California, United States

Kaiser Permanente-San Marcos

🇺🇸

San Marcos, California, United States

Kaiser Permanente-San Rafael

🇺🇸

San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara

🇺🇸

Santa Clara, California, United States

Palo Alto Medical Foundation-Santa Cruz

🇺🇸

Santa Cruz, California, United States

Kaiser Permanente-Santa Rosa

🇺🇸

Santa Rosa, California, United States

Sutter Pacific Medical Foundation

🇺🇸

Santa Rosa, California, United States

Kaiser Permanente-South San Francisco

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Stockton

🇺🇸

Stockton, California, United States

Palo Alto Medical Foundation-Sunnyvale

🇺🇸

Sunnyvale, California, United States

Gene Upshaw Memorial Tahoe Forest Cancer Center

🇺🇸

Truckee, California, United States

Kaiser Permanente Medical Center-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Vallejo

🇺🇸

Vallejo, California, United States

Kaiser Permanente-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Kaiser Permanente-Woodland Hills

🇺🇸

Woodland Hills, California, United States

UCHealth University of Colorado Hospital

🇺🇸

Aurora, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

UCHealth Memorial Hospital Central

🇺🇸

Colorado Springs, Colorado, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

AdventHealth Porter

🇺🇸

Denver, Colorado, United States

Saint Joseph Hospital - Cancer Centers of Colorado

🇺🇸

Denver, Colorado, United States

Poudre Valley Hospital

🇺🇸

Fort Collins, Colorado, United States

Banner North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Kaiser Permanente-Rock Creek

🇺🇸

Lafayette, Colorado, United States

AdventHealth Littleton

🇺🇸

Littleton, Colorado, United States

Kaiser Permanente-Lone Tree

🇺🇸

Lone Tree, Colorado, United States

AdventHealth Parker

🇺🇸

Parker, Colorado, United States

Smilow Cancer Hospital Care Center-Fairfield

🇺🇸

Fairfield, Connecticut, United States

Smilow Cancer Hospital Care Center at Saint Francis

🇺🇸

Hartford, Connecticut, United States

Yale University

🇺🇸

New Haven, Connecticut, United States

Stamford Hospital/Bennett Cancer Center

🇺🇸

Stamford, Connecticut, United States

Smilow Cancer Hospital Care Center-Trumbull

🇺🇸

Trumbull, Connecticut, United States

Helen F Graham Cancer Center

🇺🇸

Newark, Delaware, United States

Medical Oncology Hematology Consultants PA

🇺🇸

Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital

🇺🇸

Newark, Delaware, United States

Beebe Health Campus

🇺🇸

Rehoboth Beach, Delaware, United States

Elmhurst Memorial Hospital

🇺🇸

Elmhurst, Illinois, United States

MedStar Georgetown University Hospital

🇺🇸

Washington, District of Columbia, United States

MedStar Washington Hospital Center

🇺🇸

Washington, District of Columbia, United States

Lakeland Regional Health Hollis Cancer Center

🇺🇸

Lakeland, Florida, United States

Mount Sinai Medical Center

🇺🇸

Miami Beach, Florida, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center

🇺🇸

Miami, Florida, United States

Orlando Health Cancer Institute

🇺🇸

Orlando, Florida, United States

Moffitt Cancer Center

🇺🇸

Tampa, Florida, United States

Cleveland Clinic-Weston

🇺🇸

Weston, Florida, United States

Emory University Hospital/Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

Northside Hospital

🇺🇸

Atlanta, Georgia, United States

Northside Hospital-Forsyth

🇺🇸

Cumming, Georgia, United States

Memorial Health University Medical Center

🇺🇸

Savannah, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

South Georgia Medical Center/Pearlman Cancer Center

🇺🇸

Valdosta, Georgia, United States

Hawaii Cancer Care Inc - Waterfront Plaza

🇺🇸

Honolulu, Hawaii, United States

Island Urology

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Cenrer - POB I

🇺🇸

Honolulu, Hawaii, United States

Queen's Medical Center

🇺🇸

Honolulu, Hawaii, United States

Straub Clinic and Hospital

🇺🇸

Honolulu, Hawaii, United States

University of Hawaii Cancer Center

🇺🇸

Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini

🇺🇸

Honolulu, Hawaii, United States

Tripler Army Medical Center

🇺🇸

Honolulu, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Kootenai Clinic Cancer Services - Sandpoint

🇺🇸

Sandpoint, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

Rush University Medical Center

🇺🇸

Chicago, Illinois, United States

University of Chicago Comprehensive Cancer Center

🇺🇸

Chicago, Illinois, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

NorthShore University HealthSystem-Evanston Hospital

🇺🇸

Evanston, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Northwestern Medicine Cancer Center Delnor

🇺🇸

Geneva, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital

🇺🇸

Glenview, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital

🇺🇸

Highland Park, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Loyola University Medical Center

🇺🇸

Maywood, Illinois, United States

Edward Hospital/Cancer Center

🇺🇸

Naperville, Illinois, United States

UC Comprehensive Cancer Center at Silver Cross

🇺🇸

New Lenox, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

University of Chicago Medicine-Orland Park

🇺🇸

Orland Park, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Edward Hospital/Cancer Center?Plainfield

🇺🇸

Plainfield, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

UW Health Carbone Cancer Center Rockford

🇺🇸

Rockford, Illinois, United States

Central Illinois Hematology Oncology Center

🇺🇸

Springfield, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Springfield Memorial Hospital

🇺🇸

Springfield, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Northwestern Medicine Cancer Center Warrenville

🇺🇸

Warrenville, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Indiana University/Melvin and Bren Simon Cancer Center

🇺🇸

Indianapolis, Indiana, United States

Community Cancer Center East

🇺🇸

Indianapolis, Indiana, United States

Community Cancer Center South

🇺🇸

Indianapolis, Indiana, United States

Franciscan Health Indianapolis

🇺🇸

Indianapolis, Indiana, United States

Community Cancer Center North

🇺🇸

Indianapolis, Indiana, United States

Franciscan Health Mooresville

🇺🇸

Mooresville, Indiana, United States

Reid Health

🇺🇸

Richmond, Indiana, United States

Mary Greeley Medical Center

🇺🇸

Ames, Iowa, United States

McFarland Clinic - Ames

🇺🇸

Ames, Iowa, United States

McFarland Clinic - Boone

🇺🇸

Boone, Iowa, United States

Physicians' Clinic of Iowa PC

🇺🇸

Cedar Rapids, Iowa, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

🇺🇸

Clive, Iowa, United States

Iowa Methodist Medical Center

🇺🇸

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Des Moines Clinic

🇺🇸

Des Moines, Iowa, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Laurel Clinic

🇺🇸

Des Moines, Iowa, United States

McFarland Clinic - Trinity Cancer Center

🇺🇸

Fort Dodge, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center

🇺🇸

Iowa City, Iowa, United States

McFarland Clinic - Jefferson

🇺🇸

Jefferson, Iowa, United States

McFarland Clinic - Marshalltown

🇺🇸

Marshalltown, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Cancer Center of Kansas - Chanute

🇺🇸

Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City

🇺🇸

Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado

🇺🇸

El Dorado, Kansas, United States

Saint Catherine Hospital

🇺🇸

Garden City, Kansas, United States

Central Care Cancer Center - Great Bend

🇺🇸

Great Bend, Kansas, United States

Saint Rose Ambulatory and Surgery Center

🇺🇸

Great Bend, Kansas, United States

HaysMed

🇺🇸

Hays, Kansas, United States

University of Kansas Cancer Center-West

🇺🇸

Kansas City, Kansas, United States

University of Kansas Cancer Center

🇺🇸

Kansas City, Kansas, United States

Lawrence Memorial Hospital

🇺🇸

Lawrence, Kansas, United States

Kansas Institute of Medicine Cancer and Blood Center

🇺🇸

Lenexa, Kansas, United States

Minimally Invasive Surgery Hospital

🇺🇸

Lenexa, Kansas, United States

Cancer Center of Kansas-Liberal

🇺🇸

Liberal, Kansas, United States

Cancer Center of Kansas - McPherson

🇺🇸

McPherson, Kansas, United States

Cancer Center of Kansas - Newton

🇺🇸

Newton, Kansas, United States

The University of Kansas Cancer Center - Olathe

🇺🇸

Olathe, Kansas, United States

Menorah Medical Center

🇺🇸

Overland Park, Kansas, United States

University of Kansas Cancer Center-Overland Park

🇺🇸

Overland Park, Kansas, United States

Saint Luke's South Hospital

🇺🇸

Overland Park, Kansas, United States

Cancer Center of Kansas - Parsons

🇺🇸

Parsons, Kansas, United States

Mercy Hospital Pittsburg

🇺🇸

Pittsburg, Kansas, United States

Cancer Center of Kansas - Salina

🇺🇸

Salina, Kansas, United States

Salina Regional Health Center

🇺🇸

Salina, Kansas, United States

University of Kansas Health System Saint Francis Campus

🇺🇸

Topeka, Kansas, United States

Cancer Center of Kansas - Wellington

🇺🇸

Wellington, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower

🇺🇸

Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Winfield

🇺🇸

Winfield, Kansas, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Owensboro Health Mitchell Memorial Cancer Center

🇺🇸

Owensboro, Kentucky, United States

LSU Health Baton Rouge-North Clinic

🇺🇸

Baton Rouge, Louisiana, United States

Our Lady of the Lake Physician Group

🇺🇸

Baton Rouge, Louisiana, United States

Louisiana Hematology Oncology Associates LLC

🇺🇸

Baton Rouge, Louisiana, United States

Mary Bird Perkins Cancer Center

🇺🇸

Baton Rouge, Louisiana, United States

Northshore Oncology Associates-Covington

🇺🇸

Covington, Louisiana, United States

Ochsner LSU Health Monroe Medical Center

🇺🇸

Monroe, Louisiana, United States

LSU Health Sciences Center at Shreveport

🇺🇸

Shreveport, Louisiana, United States

Harold Alfond Center for Cancer Care

🇺🇸

Augusta, Maine, United States

Eastern Maine Medical Center

🇺🇸

Bangor, Maine, United States

Lafayette Family Cancer Center-EMMC

🇺🇸

Brewer, Maine, United States

New England Cancer Specialists

🇺🇸

Westbrook, Maine, United States

Mercy Medical Center

🇺🇸

Baltimore, Maryland, United States

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

🇺🇸

Baltimore, Maryland, United States

Frederick Memorial Hospital

🇺🇸

Frederick, Maryland, United States

Beverly Hospital

🇺🇸

Beverly, Massachusetts, United States

Massachusetts General Hospital Cancer Center

🇺🇸

Boston, Massachusetts, United States

Boston Medical Center

🇺🇸

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center

🇺🇸

Boston, Massachusetts, United States

Dana-Farber Cancer Institute

🇺🇸

Boston, Massachusetts, United States

Lahey Hospital and Medical Center

🇺🇸

Burlington, Massachusetts, United States

Addison Gilbert Hospital

🇺🇸

Gloucester, Massachusetts, United States

Baystate Medical Center

🇺🇸

Springfield, Massachusetts, United States

University of Michigan Comprehensive Cancer Center

🇺🇸

Ann Arbor, Michigan, United States

Wayne State University/Karmanos Cancer Institute

🇺🇸

Detroit, Michigan, United States

Henry Ford Hospital

🇺🇸

Detroit, Michigan, United States

Henry Ford Health Saint John Hospital

🇺🇸

Detroit, Michigan, United States

Henry Ford River District Hospital

🇺🇸

East China Township, Michigan, United States

OSF Saint Francis Hospital and Medical Group

🇺🇸

Escanaba, Michigan, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

🇺🇸

Grand Rapids, Michigan, United States

Trinity Health Grand Rapids Hospital

🇺🇸

Grand Rapids, Michigan, United States

Henry Ford Saint John Hospital - Academic

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Breast

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Van Elslander

🇺🇸

Grosse Pointe Woods, Michigan, United States

Allegiance Health

🇺🇸

Jackson, Michigan, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

University of Michigan Health - Sparrow Lansing

🇺🇸

Lansing, Michigan, United States

Henry Ford Saint John Hospital - Macomb Medical

🇺🇸

Macomb, Michigan, United States

Henry Ford Warren Hospital - Breast Macomb

🇺🇸

Macomb, Michigan, United States

Trinity Health Muskegon Hospital

🇺🇸

Muskegon, Michigan, United States

Corewell Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Henry Ford Rochester Hospital

🇺🇸

Rochester Hills, Michigan, United States

MyMichigan Medical Center Saginaw

🇺🇸

Saginaw, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Henry Ford Health Warren Hospital

🇺🇸

Warren, Michigan, United States

Henry Ford Warren Hospital - GLCMS

🇺🇸

Warren, Michigan, United States

University of Michigan Health - West

🇺🇸

Wyoming, Michigan, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Essentia Health Cancer Center

🇺🇸

Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center

🇺🇸

Duluth, Minnesota, United States

Miller-Dwan Hospital

🇺🇸

Duluth, Minnesota, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Lake Region Healthcare Corporation-Cancer Care

🇺🇸

Fergus Falls, Minnesota, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

University of Mississippi Medical Center

🇺🇸

Jackson, Mississippi, United States

Parkland Health Center-Bonne Terre

🇺🇸

Bonne Terre, Missouri, United States

Mercy Cancer Center - Cape Girardeau

🇺🇸

Cape Girardeau, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Centerpoint Medical Center LLC

🇺🇸

Independence, Missouri, United States

MU Health Care Goldschmidt Cancer Center

🇺🇸

Jefferson City, Missouri, United States

University Health Truman Medical Center

🇺🇸

Kansas City, Missouri, United States

Saint Luke's Hospital of Kansas City

🇺🇸

Kansas City, Missouri, United States

Heartland Hematology and Oncology Associates Incorporated

🇺🇸

Kansas City, Missouri, United States

Kansas City Veterans Affairs Medical Center

🇺🇸

Kansas City, Missouri, United States

The University of Kansas Cancer Center-South

🇺🇸

Kansas City, Missouri, United States

Research Medical Center

🇺🇸

Kansas City, Missouri, United States

University of Kansas Cancer Center - North

🇺🇸

Kansas City, Missouri, United States

University of Kansas Cancer Center - Lee's Summit

🇺🇸

Lee's Summit, Missouri, United States

Saint Luke's East - Lee's Summit

🇺🇸

Lee's Summit, Missouri, United States

Liberty Hospital

🇺🇸

Liberty, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

Saint Vincent Healthcare

🇺🇸

Billings, Montana, United States

Bozeman Health Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Saint James Community Hospital and Cancer Treatment Center

🇺🇸

Butte, Montana, United States

Benefis Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Saint Peter's Community Hospital

🇺🇸

Helena, Montana, United States

Logan Health Medical Center

🇺🇸

Kalispell, Montana, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

Community Medical Center

🇺🇸

Missoula, Montana, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

🇺🇸

Grand Island, Nebraska, United States

Nebraska Hematology and Oncology

🇺🇸

Lincoln, Nebraska, United States

Cancer Partners of Nebraska

🇺🇸

Lincoln, Nebraska, United States

Faith Regional Health Services Carson Cancer Center

🇺🇸

Norfolk, Nebraska, United States

Nebraska Methodist Hospital

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Nebraska Cancer Specialists - Omaha

🇺🇸

Omaha, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Regional West Medical Center Cancer Center

🇺🇸

Scottsbluff, Nebraska, United States

Cancer and Blood Specialists-Henderson

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson

🇺🇸

Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson

🇺🇸

Henderson, Nevada, United States

GenesisCare USA - Henderson

🇺🇸

Henderson, Nevada, United States

University Medical Center of Southern Nevada

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Las Vegas

🇺🇸

Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine

🇺🇸

Las Vegas, Nevada, United States

Ann M Wierman MD LTD

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley

🇺🇸

Las Vegas, Nevada, United States

University Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Wentworth-Douglass Hospital

🇺🇸

Dover, New Hampshire, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

🇺🇸

Lebanon, New Hampshire, United States

Dartmouth Cancer Center - Manchester

🇺🇸

Manchester, New Hampshire, United States

Saint Joseph Hospital

🇺🇸

Nashua, New Hampshire, United States

Dartmouth Cancer Center - Nashua

🇺🇸

Nashua, New Hampshire, United States

Veterans Adminstration New Jersey Health Care System

🇺🇸

East Orange, New Jersey, United States

Hackensack University Medical Center

🇺🇸

Hackensack, New Jersey, United States

Saint Barnabas Medical Center

🇺🇸

Livingston, New Jersey, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

Lovelace Medical Center-Saint Joseph Square

🇺🇸

Albuquerque, New Mexico, United States

Southwest Gynecologic Oncology Associates Inc

🇺🇸

Albuquerque, New Mexico, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Hematology Oncology Associates of Central New York-Auburn

🇺🇸

Auburn, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Hematology Oncology Associates of CNY at Camillus

🇺🇸

Camillus, New York, United States

Hematology Oncology Associates of Central New York-East Syracuse

🇺🇸

East Syracuse, New York, United States

Glens Falls Hospital

🇺🇸

Glens Falls, New York, United States

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

🇺🇸

New York, New York, United States

Rochester General Hospital

🇺🇸

Rochester, New York, United States

University of Rochester

🇺🇸

Rochester, New York, United States

Stony Brook University Medical Center

🇺🇸

Stony Brook, New York, United States

State University of New York Upstate Medical University

🇺🇸

Syracuse, New York, United States

UNC Lineberger Comprehensive Cancer Center

🇺🇸

Chapel Hill, North Carolina, United States

Southeastern Medical Oncology Center-Clinton

🇺🇸

Clinton, North Carolina, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro

🇺🇸

Goldsboro, North Carolina, United States

Wayne Memorial Hospital

🇺🇸

Goldsboro, North Carolina, United States

Margaret R Pardee Memorial Hospital

🇺🇸

Hendersonville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville

🇺🇸

Jacksonville, North Carolina, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Altru Cancer Center

🇺🇸

Grand Forks, North Dakota, United States

UHHS-Chagrin Highlands Medical Center

🇺🇸

Beachwood, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Dayton Physicians LLC-Miami Valley South

🇺🇸

Centerville, Ohio, United States

Miami Valley Hospital South

🇺🇸

Centerville, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

MetroHealth Medical Center

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Foundation

🇺🇸

Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Good Samaritan Hospital - Dayton

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital

🇺🇸

Dayton, Ohio, United States

Dayton Physician LLC - Englewood

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Armes Family Cancer Center

🇺🇸

Findlay, Ohio, United States

Blanchard Valley Hospital

🇺🇸

Findlay, Ohio, United States

Orion Cancer Care

🇺🇸

Findlay, Ohio, United States

Cleveland Clinic Cancer Center Independence

🇺🇸

Independence, Ohio, United States

Greater Dayton Cancer Center

🇺🇸

Kettering, Ohio, United States

Kettering Medical Center

🇺🇸

Kettering, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Cleveland Clinic Cancer Center Mansfield

🇺🇸

Mansfield, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

Hillcrest Hospital Cancer Center

🇺🇸

Mayfield Heights, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

University Hospitals Parma Medical Center

🇺🇸

Parma, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

North Coast Cancer Care

🇺🇸

Sandusky, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center

🇺🇸

Sandusky, Ohio, United States

Cleveland Clinic Cancer Center Strongsville

🇺🇸

Strongsville, Ohio, United States

ProMedica Flower Hospital

🇺🇸

Sylvania, Ohio, United States

University of Toledo

🇺🇸

Toledo, Ohio, United States

South Pointe Hospital

🇺🇸

Warrensville Heights, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

Cleveland Clinic Wooster Family Health and Surgery Center

🇺🇸

Wooster, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Kaiser Permanente Northwest

🇺🇸

Portland, Oregon, United States

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

Jefferson Abington Hospital

🇺🇸

Abington, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Saint Luke's University Hospital-Bethlehem Campus

🇺🇸

Bethlehem, Pennsylvania, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Ephrata Cancer Center

🇺🇸

Ephrata, Pennsylvania, United States

Ephrata Community Hospital

🇺🇸

Ephrata, Pennsylvania, United States

UPMC Hillman Cancer Center Erie

🇺🇸

Erie, Pennsylvania, United States

Adams Cancer Center

🇺🇸

Gettysburg, Pennsylvania, United States

WellSpan Medical Oncology and Hematology

🇺🇸

Hanover, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Penn State Milton S Hershey Medical Center

🇺🇸

Hershey, Pennsylvania, United States

Fox Chase Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Allegheny General Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

West Penn Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

University of Pittsburgh Cancer Institute (UPCI)

🇺🇸

Pittsburgh, Pennsylvania, United States

Geisinger Cancer Services-Pottsville

🇺🇸

Pottsville, Pennsylvania, United States

Reading Hospital

🇺🇸

West Reading, Pennsylvania, United States

Wexford Health and Wellness Pavilion

🇺🇸

Wexford, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

UPMC Susquehanna

🇺🇸

Williamsport, Pennsylvania, United States

WellSpan Health-York Cancer Center

🇺🇸

York, Pennsylvania, United States

WellSpan Health-York Hospital

🇺🇸

York, Pennsylvania, United States

Newport Hospital

🇺🇸

Newport, Rhode Island, United States

Rhode Island Hospital

🇺🇸

Providence, Rhode Island, United States

Miriam Hospital

🇺🇸

Providence, Rhode Island, United States

Utah Valley Regional Medical Center

🇺🇸

Provo, Utah, United States

AnMed Health Cancer Center

🇺🇸

Anderson, South Carolina, United States

Roper Hospital

🇺🇸

Charleston, South Carolina, United States

Charleston Oncology - Roper

🇺🇸

Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-North Charleston

🇺🇸

Charleston, South Carolina, United States

Bon Secours Saint Francis Hospital

🇺🇸

Charleston, South Carolina, United States

Charleston Oncology - Saint Francis

🇺🇸

Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-West Ashley

🇺🇸

Charleston, South Carolina, United States

Saint Francis Cancer Center

🇺🇸

Greenville, South Carolina, United States

Lowcountry Hematology Oncology PA-Mount Pleasant

🇺🇸

Mount Pleasant, South Carolina, United States

Rapid City Regional Hospital

🇺🇸

Rapid City, South Dakota, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

The West Clinic - Wolf River

🇺🇸

Germantown, Tennessee, United States

The West Clinic - Mid-Town

🇺🇸

Memphis, Tennessee, United States

University of Tennessee Health Science Center

🇺🇸

Memphis, Tennessee, United States

Vanderbilt University/Ingram Cancer Center

🇺🇸

Nashville, Tennessee, United States

Texas Oncology - Central Austin Cancer Center

🇺🇸

Austin, Texas, United States

Baylor University Medical Center

🇺🇸

Dallas, Texas, United States

M D Anderson Cancer Center

🇺🇸

Houston, Texas, United States

American Fork Hospital / Huntsman Intermountain Cancer Center

🇺🇸

American Fork, Utah, United States

Sandra L Maxwell Cancer Center

🇺🇸

Cedar City, Utah, United States

Logan Regional Hospital

🇺🇸

Logan, Utah, United States

Intermountain Medical Center

🇺🇸

Murray, Utah, United States

McKay-Dee Hospital Center

🇺🇸

Ogden, Utah, United States

Saint George Regional Medical Center

🇺🇸

Saint George, Utah, United States

Utah Cancer Specialists-Salt Lake City

🇺🇸

Salt Lake City, Utah, United States

Huntsman Cancer Institute/University of Utah

🇺🇸

Salt Lake City, Utah, United States

LDS Hospital

🇺🇸

Salt Lake City, Utah, United States

South Jordan Health Center

🇺🇸

South Jordan, Utah, United States

Central Vermont Medical Center/National Life Cancer Treatment

🇺🇸

Berlin, Vermont, United States

University of Vermont Medical Center

🇺🇸

Burlington, Vermont, United States

University of Vermont and State Agricultural College

🇺🇸

Burlington, Vermont, United States

Centra Alan B Pearson Regional Cancer Center

🇺🇸

Lynchburg, Virginia, United States

Virginia Cancer Institute

🇺🇸

Richmond, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center

🇺🇸

Richmond, Virginia, United States

VCU Community Memorial Health Center

🇺🇸

South Hill, Virginia, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Kaiser Permanente Washington

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

United Hospital Center

🇺🇸

Bridgeport, West Virginia, United States

West Virginia University Charleston Division

🇺🇸

Charleston, West Virginia, United States

West Virginia University Healthcare

🇺🇸

Morgantown, West Virginia, United States

Camden Clark Medical Center

🇺🇸

Parkersburg, West Virginia, United States

Langlade Hospital and Cancer Center

🇺🇸

Antigo, Wisconsin, United States

Aurora Cancer Care-Southern Lakes VLCC

🇺🇸

Burlington, Wisconsin, United States

Marshfield Clinic-Chippewa Center

🇺🇸

Chippewa Falls, Wisconsin, United States

Marshfield Clinic Cancer Center at Sacred Heart

🇺🇸

Eau Claire, Wisconsin, United States

Saint Agnes Hospital/Agnesian Cancer Center

🇺🇸

Fond Du Lac, Wisconsin, United States

Aurora Health Center-Fond du Lac

🇺🇸

Fond Du Lac, Wisconsin, United States

Aurora Health Care Germantown Health Center

🇺🇸

Germantown, Wisconsin, United States

Aurora Cancer Care-Grafton

🇺🇸

Grafton, Wisconsin, United States

Green Bay Oncology at Saint Vincent Hospital

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay

🇺🇸

Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's

🇺🇸

Green Bay, Wisconsin, United States

Aurora BayCare Medical Center

🇺🇸

Green Bay, Wisconsin, United States

Aurora Cancer Care-Kenosha South

🇺🇸

Kenosha, Wisconsin, United States

Gundersen Lutheran Medical Center

🇺🇸

La Crosse, Wisconsin, United States

University of Wisconsin Carbone Cancer Center - University Hospital

🇺🇸

Madison, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette

🇺🇸

Marinette, Wisconsin, United States

Bay Area Medical Center

🇺🇸

Marinette, Wisconsin, United States

Marshfield Medical Center-Marshfield

🇺🇸

Marshfield, Wisconsin, United States

Froedtert Menomonee Falls Hospital

🇺🇸

Menomonee Falls, Wisconsin, United States

Aurora Cancer Care-Milwaukee

🇺🇸

Milwaukee, Wisconsin, United States

Ascension Southeast Wisconsin Hospital - Saint Joseph Campus

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Saint Luke's Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Marshfield Medical Center - Minocqua

🇺🇸

Minocqua, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Oconto Falls

🇺🇸

Oconto Falls, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Aurora Cancer Care-Racine

🇺🇸

Racine, Wisconsin, United States

Lakeview Medical Center-Marshfield Clinic

🇺🇸

Rice Lake, Wisconsin, United States

Marshfield Medical Center-Rice Lake

🇺🇸

Rice Lake, Wisconsin, United States

HSHS Saint Nicholas Hospital

🇺🇸

Sheboygan, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan

🇺🇸

Sheboygan, Wisconsin, United States

Aspirus Cancer Care - Stevens Point

🇺🇸

Stevens Point, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Sturgeon Bay

🇺🇸

Sturgeon Bay, Wisconsin, United States

Aurora Medical Center in Summit

🇺🇸

Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers

🇺🇸

Two Rivers, Wisconsin, United States

Aspirus Regional Cancer Center

🇺🇸

Wausau, Wisconsin, United States

Marshfield Clinic-Wausau Center

🇺🇸

Wausau, Wisconsin, United States

Aurora Cancer Care-Milwaukee West

🇺🇸

Wauwatosa, Wisconsin, United States

Aurora West Allis Medical Center

🇺🇸

West Allis, Wisconsin, United States

Marshfield Medical Center - Weston

🇺🇸

Weston, Wisconsin, United States

Aspirus Cancer Care - Wisconsin Rapids

🇺🇸

Wisconsin Rapids, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center

🇺🇸

Wisconsin Rapids, Wisconsin, United States

Big Horn Basin Cancer Center

🇺🇸

Cody, Wyoming, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

BCCA-Vancouver Cancer Centre

🇨🇦

Vancouver, British Columbia, Canada

The Vitalite Health Network - Dr Leon Richard Oncology Centre

🇨🇦

Moncton, New Brunswick, Canada

Royal Victoria Regional Health Centre

🇨🇦

Barrie, Ontario, Canada

Juravinski Cancer Centre at Hamilton Health Sciences

🇨🇦

Hamilton, Ontario, Canada

Kingston Health Sciences Centre

🇨🇦

Kingston, Ontario, Canada

Grand River Regional Cancer Centre at Grand River Hospital

🇨🇦

Kitchener, Ontario, Canada

London Regional Cancer Program

🇨🇦

London, Ontario, Canada

Trillium Health Partners - Credit Valley Hospital

🇨🇦

Mississauga, Ontario, Canada

Lakeridge Health Oshawa

🇨🇦

Oshawa, Ontario, Canada

Ottawa Hospital and Cancer Center-General Campus

🇨🇦

Ottawa, Ontario, Canada

Algoma District Cancer Program Sault Area Hospital

🇨🇦

Sault Ste Marie, Ontario, Canada

Thunder Bay Regional Health Science Centre

🇨🇦

Thunder Bay, Ontario, Canada

Odette Cancer Centre- Sunnybrook Health Sciences Centre

🇨🇦

Toronto, Ontario, Canada

University Health Network-Princess Margaret Hospital

🇨🇦

Toronto, Ontario, Canada

Windsor Regional Cancer Centre

🇨🇦

Windsor, Ontario, Canada

Hopital de la Cite-de-la-Sante

🇨🇦

Laval, Quebec, Canada

The Research Institute of the McGill University Health Centre (MUHC)

🇨🇦

Montreal, Quebec, Canada

CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)

🇨🇦

Quebec City, Quebec, Canada

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

🇨🇦

Sherbrooke, Quebec, Canada

Allan Blair Cancer Centre

🇨🇦

Regina, Saskatchewan, Canada

Saskatoon Cancer Centre

🇨🇦

Saskatoon, Saskatchewan, Canada

Saint Vincent's University Hospital

🇮🇪

Dublin, Co Dublin, Ireland

University College Hospital Galway

🇮🇪

Galway, Co Galway, Ireland

University Hospital Waterford

🇮🇪

Waterford, Co Waterford, Ireland

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