Effect of methylene blue(drug used in very low blood pressure) in critically ill patients
- Conditions
- Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services
- Registration Number
- CTRI/2021/12/038542
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients older than 18 years diagnosed with septic shock during their ICU stay whose relatives give informed consent for the study will be considered for enrolment.
Within 24hrs of septic shock
Patients whose relatives refuse to give consent for the study.
Unstable coronary artery syndrome (acute myocardial infarction during this episode of shock based on the combination of history, electrocardiogram and enzyme changes) or underlying cardiac dysfunction [cardiac index (CI) <2.2 l/min/m2]
Stroke or head injury.
Chronic renal failure on maintenance dialysis.
Malignancy or other irreversible disease or condition for which mortality was estimated to be very high (defined by investigator),
Acute mesenteric ischemia either proven or suspected
Raynaudâ??s phenomenon
Pregnancy
Organ transplantation.
Known hypersensitivity to norepinephrine or methylene blue -G 6PD deficiency.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method