Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury
Completed
- Conditions
- Drug Induced Liver Injury
- Registration Number
- NCT01000766
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Brief Summary
The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.
- Detailed Description
Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- ALT > 200 IU/L at presentation to UNC Hospitals
- Drug induced liver injury considered likely by admitting medical staff
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of North Carolina
🇺🇸Chapel Hill, North Carolina, United States