EUCTR2007-000053-62-GBActive, not recruitingNot Applicable
The effects of helium-oxygen gas mixture (Heliox) on airway pressures in mechanically ventilated adult patients with acute lung injury - Chertsey Heliox trial
Ashford & St. Peter's Hospitals NHS Trust0 sitesStarted: March 25, 2008Last updated:
Conditions
Drugs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Patients who meet the American-European Consensus Conference Criteria for ALI (acute onset, bilateral pulmonary infiltrates are present on chest X-ray) and PaO2:FiO2 < 35 on positive end-expiratory pressure (PEEP) of >=5 cm H2O.
- •Patients willl be enrolled within 48 hours of ALI onset
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- •<18 years of age
- •participation in other trials
- •>48 hours of mechanical ventilation before inclusion
- •severe prexisting heart disease or left heart failure
- •unstable patients requiring high dosage of vasopressosrs (noradrenaline > 0.8 mcg/kg/min and/or dobutamine>20 mcg/kg/min)
- •failure to obtain written patient's next of kin assent
Investigators
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