Clinical study on optimal strategy for treatment of Non-active Graves ophthalmopathy
- Conditions
- Graves ophthalmopathy
- Registration Number
- ITMCTR2000003668
- Lead Sponsor
- onghua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Typical ocular symptoms;
2. Protrusion degree & GT;18mm(including unilateral protruding eye);
3. Inactive protrusion is defined as the clinical scoring standard recommended by the 2008 Chinese Guidelines for the Diagnosis and treatment of thyroid diseases;
4. Refuse operation patients;
5. Patients with Graves' disease and normal serum thyroid hormone levels (FT3 and FT4) for at least two months;
6. Informed consent, willing to receive treatment and with good predictive compliance, age 18-70 years old;
7. TCM syndrome differentiation indicates deficiency of Yang qi and blockage of phlegm and blood stasis.
1. Shortness of eyes caused by other causes: case of shortness of eyes, orbital inflammatory pseudotumor, carotid cavernous fistula or dural cavernous sinus short circuit, extraocular muscle lymphoid tumor, primary orbital tumor, eye metastasis tumor, intracranial tumor and other diseases.
2. Clinical score of protruding eye activity >= 3.
3. Psychopaths.
4. Patients with severe primary and secondary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic systems, and with a tendency of hyperthyroidism crisis.
5. Women who are pregnant or breastfeeding.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method proptosis;
- Secondary Outcome Measures
Name Time Method Orbital computed tomography;vision;TCM syndrome score;