Cognitive function and psychological capability in Post-Covid-19 syndrome

Conditions: F06.7
Mild cognitive disorder
Post-Covid-Syndrome ICD-10:U09.9

Registration Number: DRKS00029508

Lead Sponsor: Klinik für Allgemeine Psychiatrie, Universitätsklinikum Heidelberg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 128

Inclusion Criteria

Ability to provide informed consent, age = 18 years, history of SARS-CoV-2 infection.

Group 1: new or worsened psychiatric symptoms concerning affectivity, energy levels and tiredness, cognition or anxiety and stress related problems that have started after SARS-CoV-2 infection and are persistent on the day of examination, but no shorter than 12 weeks (so called post-covid-syndrom).

Group 2: no residual symptoms of after SARS-CoV-2 infection.

Exclusion Criteria

1. unable to provide informed consent
2. acute, severe somatic or psychiatric illnesses, such as:
psychiatric:
- acute psychosis
- acute suicidal ideation
- acute mania
- acute intoxication
- severe anxiety/OCD/depressive symptoms impeding the examination
somatic:
-acute neurologic or somatic illnesses that require medical attention such as acute infections, pain or injuries
-persistent or chronic conditions that may impede the examination (particularly sensory or motor deficits)

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
europsycholocial performance measured as sum score (z-score) in terms of a neuropsychological assessment, consisting of the dimensions attention (alertness and divided attention, psychomotor speed), concentration (d2-R), memory (visospatial memory, verbal memory), executive function (task switching, planning and decision making, response inhibition, verbal fluency)<br><br>

Secondary Outcome Measures

Name	Time	Method
Quality of life, depressive symptoms, subjectiv mental performance, fatigue symptoms, assessed by application of standardized questionnaires (WHOQoL, BDI-II, Flei, FQ-D).<br><br>