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Social Cognition in Longstanding Psychosis

Terminated
Conditions
Major Depression With Psychotic Features
Schizophrenia
Schizoaffective Disorder
Bipolar Disorder With Psychotic Features
Psychosis Not Otherwise Specified (NOS)
Registration Number
NCT01624831
Lead Sponsor
University of Arizona
Brief Summary

In the current study, the investigators propose to measure the five domains of social cognition identified by the National Institute of Mental Health (NIMH) as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Detailed Description

There is growing evidence that individuals with longstanding psychotic disorders suffer from deficits in social cognition (i.e., the cognitive skills needed to successfully navigate social interactions). However, to date, there have been few attempts to measure multiple components of social cognition within the same population of individuals with psychosis. Thus, the interrelationships between various aspects of social cognition remain unclear. In the current study, the investigators propose to measure the five domains of social cognition identified by NIMH as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
9
Inclusion Criteria
  • Diagnosis of a schizophrenia spectrum disorder or an affective disorder with psychotic features per the Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revised (DSM-IV-TR) criteria using the Structured Clinical Interview for the DSM-IV.
  • Duration of psychotic symptoms greater than or equal to 5 years determined using the Symptom Onset in Schizophrenia Inventory
  • Age 18-75
  • No evidence of mental retardation.
  • Able to provide informed consent as evidenced by passing the informed consent quiz with a score of 80% or greater.
  • Fluent in English as assessed per self-report from participant
Exclusion Criteria
  • Unwilling or unable to complete study assessments (e.g., unable to read self-report questionnaires)
  • Subject is currently pregnant per subject's report

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Emotion RecognitionBaseline and 6 months

Change from baseline to 6 month assessment in ability to recognize emotions displayed by others assessed using the Facial Emotion Identification Test

Attribution StyleBaseline and 6 months

Change from baseline to 6 month assessment in tendency to attribute events that occur to situational, personal, or internal factors assessed using the Internal, Personal, and Situational Attributions Questionnaire

Social PerceptionBaseline and 6 months

Change from baseline to 6 month assessment in ability to understand concrete and abstract components of everyday social interactions assessed using the Social Cues Recognition Test

Social KnowledgeBaseline and 6 months

Change from baseline to 6 month assessment in knowledge of goals and actions associated with familiar and unfamiliar social activities assessed using the Situational Features Recognition Test

Theory of MindBaseline and 6 months

Change from baseline to 6 month assessment in ability to identify the mental states of other individuals assessed using the Hinting Test

Secondary Outcome Measures
NameTimeMethod
AnxietyBaseline and 6 months

Change from baseline to 6 month assessment in anxiety assessed using the Beck Anxiety Inventory

DepressionBaseline and 6 months

Change from baseline to 6 month assessment in depression assessed using the Beck Depression Inventory

PsychosisBaseline and 6 months

Change from baseline to 6 month assessment in severity of positive and negative psychotic symptoms assessed using the Positive and Negative Syndrome Scale

Social FunctioningBaseline and 6 months

Change from baseline to 6 month assessment in level of social functioning assessed using the Social Functioning Scale

Service UtilizationBaseline and 6 months

Change from baseline to 6 month assessment in utilization of medical services assessed using the Service Utilization Record Form

Self-Determination Needs SatisfactionBaseline and 6 months

Change from baseline to 6 month assessment in ability to fulfill basic needs for autonomy, competence, and relatedness assessed using the Basic Psychological Needs Scale

Locus of ControlBaseline and 6 months

Change from baseline to 6 month assessment in perception of one's ability to control events in the environment assessed using the Multidimensional Locus of Control Scale

Cognitive representation of illnessBaseline and 6 months

Change from baseline to 6 month assessment in understanding of nature of psychotic illness assessed using the Illness Perception Questionnaire

Emotional AwarenessBaseline and 6 months

Change from baseline to 6 month assessment in awareness of one's own emotions as well as emotions of others assessed using the Levels of Emotional Awareness Scale

MindfulnessBaseline and 6 months

Change from baseline to 6 month assessment in awareness and acceptance of feelings and events assessed using the Philadelphia Mindfulness Scale

Medication adherenceBaseline and 6 months

Change from baseline to 6 month assessment in adherence to psychiatric medication assessed using the Medication Adherence Rating Scale

Neuropsychological functioningBaseline and 6 months

Change from baseline to 6 month assessment in neuropsychological functioning assessed using the MATRICS Consensus Cognitive Battery

Social SupportBaseline and 6 months

Change from baseline to 6 month assessment in level of social support assessed using the Measure of Perceived Support

Illness UncertaintyBaseline and 6 months

Change from baseline to 6 month assessment in uncertainty with regard to cause, course, and treatment of illness assessed using the Mischel Uncertainty in Illness Scale

Relationship with familial caregiversBaseline and 6 months

Change from baseline to 6 month assessment in relationship with familial caregivers assessed using the Perception of Parents Scale

Self-efficacyBaseline and 6 months

Change from baseline to 6 month assessment in confidence with regard to control of psychotic symptoms assessed using the Self-Efficacy Scale for Schizophrenia

Experience of StigmaBaseline and 6 months

Change from baseline to 6 month assessment in experience of stigma with regard to mental illness assessed using the Stigma Questionnaire

quality of lifeBaseline and 6 months

Change from baseline to 6 month assessment in quality of life assessed using the WHO Quality of Life Scale-Brief

stage of recoveryBaseline and 6 months

Change from baseline to 6 month assessment in stage of recovery with regard to mental illness assessed using the Stages of Recovery Instrument

Coping skillsBaseline and 6 months

Change from baseline to 6 month assessment in level of coping skills assessed using the Ways of Coping Questionnaire

Time perspectiveBaseline and 6 months

Change from baseline to 6 month assessment in time orientation assessed using the Zimbardo Time Perspective Instrument

Trial Locations

Locations (1)

University of Arizona Department of Psychiatry

🇺🇸

Tucson, Arizona, United States

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