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Segmentectomy vs Lobectomy

Active, not recruiting
Conditions
Non-small Cell Lung Cancer Stage I
Surgery
Registration Number
NCT06180239
Lead Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Brief Summary

Actual indications for stage Ia NSCLC patients suggest lobectomy and lymphadenectomy. On the other hand, recent studies reported non-inferiority of segmentectomy in case of nodule \< 2cm or with ground glass appearance at computed tomography.

However, most of these studies did not report specifical analysis on kind of segmentectomy (single or multiple) and kind of lobectomy. Moreover, a specific study on solid nodules only is still missing.

For these reasons, the effectiveness of segmentectomy instead lobectomy for every kind of segment or tumor is still to be defined.

Aim of this study is to analyze survival outcome in patients underwent single or multiple segmentectomy compared to lobectomy in stage I non small cell lung cancer.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
800
Inclusion Criteria
  • Adenocarcinoma or squamous cell carcinoma
  • cStage cIA with or without nodal upstaging
  • lymphoadenectomy
  • age > 18 years old
  • Radical resection
  • anatomical resection (lobectomy or segmentectomy)
  • PET CT done
Exclusion Criteria
  • Nodal or distant metastasis confirmed before surgery
  • Pure solid GGO
  • Follow up < 12 months
  • Bilobectomy/pneumonectomy
  • Trans fissure tumor
  • Multiple lung tumors

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
disease free survival1 YEAR

Time between surgery and recurrence appearance

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Marco Chiappetta

🇮🇹

Roma, Italy

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