Comparison comparatively less amount of fluid therapy and liberal fluid therapy on kidney function parameters in patients who are taken for Major Abdominal and Gynaecological: A prospective Randomised Clinical Trial

Not Applicable

• Conditions: Health Condition 1: C19- Malignant neoplasm of rectosigmoidjunction

• Registration Number: CTRI/2021/04/032579
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

We will include the following patients: Adults (>=18 years) of either sex undergoing elective major Abdominal & Gynaecological surgeries.

All these patients have increased risk of postoperative complications, defined by at least one of the following criteria:

age >=70 years

known or documented history of coronary artery disease

known or documented history of heart failure

diabetes currently treated with an oral hypoglycemic agent and/or insulin

preoperative serum creatinine >200 μmol/L ( >2.8 mg/dL)

morbid obesity (body mass index [BMI] >=35 kg/m2)

preoperative serum albumin <30 g/L

anaerobic threshold (if performed) <12 mL/kg/min

or two or more of the following risk factors:

â??â??American Society of Anesthesiologists (ASA) physical status 3 or 4

â??â??chronic respiratory disease

â??â??obesity (BMI 30â??35 kg/m2)

â??â??aortic or peripheral vascular disease

â??â??preoperative hemoglobin <100 g/L

â??â??preoperative serum creatinine 150â??199 μmol/L ( >1.7 mg/dL)

â??â??anaerobic threshold (if performed) 12â??14 mL/kg/min.

Exclusion Criteria

We will apply the following exclusion criteria: Urgent or time-critical surgery

ASA physical status 5

Chronic renal failure requiring dialysis

Liver resection

Minor or intermediate surgery,

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change serum creatinine and cystatin -CTimepoint: in 72 hours

Secondary Outcome Measures

Name	Time	Method
Delta change in serum sodium, potassium and chloride levelsTimepoint: with in 48 hours