Study of combination therapy by oral isotretinoin, local clobetasol, and tacrolimus in comparison to local clobetasol, and tacrolimus on patients with Frontal Fibrosing Alopecia
Not Applicable
Recruiting
- Conditions
- Frontal Fibrosing Alopecia.Lichen planopilaris
- Registration Number
- IRCT2017091736173N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
patients with clinicopathologically proven FFA, older than 18 years
Exclusion criteria: 1. pregnancy 2. inability to participate or follow the trial 3. severe hypertriglyceridemia 4. liver enzyme disturbance 5. consumption of immunosuppressant or another kind of LLP or FFA therapies during recent 3 months
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frontal Fibrosing Alopecia Severity Index (FFASI). Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Questionaire.;Hair amount and density. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Fotofinder.;Clinical presentations (itching and irritation). Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Patient asking.
- Secondary Outcome Measures
Name Time Method Perifollicular scaling. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Trichoscope.;Perifulicular erythema. Timepoint: before trial and in 2, 4, and 6 months later. Method of measurement: Trichoscope.