Women's Hospital of Nanjing Medical University
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- insulin
研究概览
简要总结
Breastfeeding could effectively be associated with a lower risk of future type 2 diabetes (T2D) in women with gestational diabetes mellitus (GDM), but the short-term protective impact of puerperal breastfeeding on maternal metabolic recovery of GDM women remains unascertained. The investigators recruited GDM participants at 6-9 weeks postpartum and retrieved clinical diagnoses of GDM from electronic medical records. Feeding patterns were collected via phone calls. Glucose metabolism parameters and lipid profiling were performed on fasting plasma samples collected from patients 6-9 weeks postpartum (20 breastfeeding cases vs. 15 formula feeding cases).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •18-35 years old;
- •gestational age greater than 37 weeks;
- •Body Mass Index (BMI) before pregnancy 18.5-28kg/m2;
- •Have normal listening and speaking skills, can communicate, and are willing to participate in this study.
排除标准
- •abnormal glucose metabolism or diabetes has been diagnosed before pregnancy;
- •assisted reproduction;
- •GDM patients requiring drug treatment;
- •The use of blood lipid regulation drugs;
- •other pregnancy complications and complications;
- •Suffering from heart, malignant tumor, kidney and other major organ diseases;
- •associated with neurological dysfunction and cognitive impairment;
- •Failure to cooperate with follow-up observers.
结局指标
主要结局
insulin
时间窗: At 6-8 weeks postpartum
insulin (mU/L) determined with human ELISA kits
HOMA-IR
时间窗: At 6-8 weeks postpartum
fasting glucose and fasting glucose will be combined to report HOMA-IR
glucose
时间窗: At 6-8 weeks postpartum
glucose (mmol/L) determined with human ELISA kits
c-peptide
时间窗: At 6-8 weeks postpartum
c-peptide (ng/m) determined with human ELISA kits
次要结局
未报告次要终点
研究者
Xirong Guo
Professor
Nanjing Medical University