1 Year Post Discharge Prognostic Model From the National Heart Failure Audit (NHFA)

• Conditions: Heart Failure
• Interventions: Other: Heart Failure Management

• Registration Number: NCT02353481
• Lead Sponsor: University College, London

Brief Summary

The aim of the study is to develop and assess a prognostic model for patient's survival up to 1 year after unscheduled acute heart failure hospital admission in England and Wales.

Detailed Description

There is a need for a prognostic model for 1 year survival of patients discharged alive after an unscheduled hospital admission for heart failure. This study aims to develop and validate a prognostic model that will enable management planning and facilitate the identification of therapeutic needs or targets. Also, it will assist care providers to predict or quantify patients' survival based on their baseline characteristics.

The National Heart Failure Audit (NHFA) held by National Institute for Cardiovascular Outcomes Research (NICOR) is one of the largest available national heart failure registry. It includes data from unscheduled heart failure admissions in England and Wales. In the audit, heart failure diagnosis is defined as a diagnosis that has been confirmed by imaging or brain natriuretic peptide (BNP) measurement. This study will use NHFA data to develop and validate the proposed model.

Study Timeline

• Study Start: 2012-04
• Study First Submitted: 2015-01-28
• Study First Submitted QC: 2015-01-28
• Status Verified: 2015-02
• Study First Posted: 2015-02-02
• Last Update Submitted: 2015-02-02
• Last Update Posted: 2015-02-03
• Primary Completion: 2015-03
• Study Completion: 2015-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 63320

Inclusion Criteria

• aged 18 and above
• survived to discharge
• have mortality status at 1 year post-discharge

Exclusion Criteria

Non-index heart failure admissions during the study period will be excluded from the study sample.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Heart Failure	Heart Failure Management	All patients in the audit that meets the eligibility criteria

Primary Outcome Measures

Name	Time	Method
All-cause mortality	1 year

Trial Locations

Locations (1)

University College London; 🇬🇧 London, United Kingdom