Active prevention and treatment of maternal sepsis in health care facilities in Malawi and Uganda

Not Applicable

• Conditions: Maternal Sepsis; Infections and Infestations

• Registration Number: ISRCTN42347014
• Lead Sponsor: niversity of Liverpool

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-10-10
• Last Update Posted: 18 September 2023
• Study Completion: 2024-07-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 172560

Inclusion Criteria

Cluster: Health care facilities offering maternity care, will be included as a cluster following the completion of a successful feasibility report requiring the minimum prerequisites of:
1. A minimum of 1500 births per year
2. Providers of comprehensive emergency obstetric care (e.g., able to perform caesarean sections and blood transfusions)
3. Completed the site readiness assessment process

Research participant:
Healthcare workers and managers responsible for the care of women during or after pregnancy in the study facility

Exclusion Criteria

Cluster exclusion criteria:
Facilities not willing to participate in the study

Research participant exclusion criteria:
Healthcare workers not willing to consent to participation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite outcome of infection-related maternal mortality, infection-related maternal near-miss and severe infection-related morbidity (deep surgical site infection or body cavity infection) measured by the collection of daily observations from routine health facility records from all women who are admitted to the healthcare facility, during pregnancy or within 42 days of delivery with a severe infection from the baseline phase to the end of cluster participation