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A Novel Point-to-care Method for Fast Evaluation of Viscoelastic Hemostasis Analysis

Recruiting
Conditions
Perioperative Period
Interventions
Procedure: Blood specimen collection
Registration Number
NCT05921799
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Brief Summary

This study compares the results of the existing coagulation monitoring technology to the Ultrasound-based viscoelastic hemostasis analysis, a new method, using small amount of extra blood obtained during routine blood draws in surgery patients.

Detailed Description

Ultrasound-based viscoelastic hemostasis analysis is a novel POC diagnostic method, which is suitable for use in surgical care settings.

The novel viscoelastic hemostasis analysis uses ultrasound guided waves to characterize the dynamic changes in viscoelastic properties of a blood sample during coagulation and clot lysis, which will be the surgical assay for monitoring hemostasis during major surgical procedures in adult patients.

This single-center, prospective, observational pilot study will evaluate the analytical performance as well as compared to standard coagulation tests and comparable measures using conventional viscoelastic testing methods.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Subject is scheduled for surgery with general surgery
  • Subject is 18 years or order
  • Subject requires routine TEG measurement
Exclusion Criteria
  • Subject is unwilling to participate
  • Subject is unable to sign a consent form
  • Subject is unsuitable for blood drawing
  • Subject is unsuitable for this study in the opinion of the anesthesiologist

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
General anesthesia PatientsBlood specimen collectionSubjects experiencing general anesthesia such that viscoelastic testing is performed to assess coagulopathy.
Primary Outcome Measures
NameTimeMethod
Comparison of the novel viscoelastic hemostasis analysis results to TEG results1 day

Coagulation function assessed by the novel viscoelastic hemostasis analysis and TEG

Comparison of the novel viscoelastic hemostasis analysis results to standard coagulation test results1 day

Coagulation function assessed by the novel viscoelastic hemostasis analysis and standard coagulation test

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

The Second Affiliated Hospital of Zhejiang University anesthesiology department

🇨🇳

Hangzhou, Zhejiang, China

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