H2O/O2-PET for determination of tumor hypoxia before and during radiotherapy in patients with head and neck cancer
Not Applicable
Recruiting
- Conditions
- C00-C14Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- DRKS00006058
- Lead Sponsor
- niversitätsSpital Zürich
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Age = 18 years
- Signed Informed Consent
- 10 patients with histologically proven squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx and larynx
- Tumors large enough for PET imaging according to the judgement of the treating physicians
- Radio(chemo)therapy or radiotherapy in combination with cetuximab with curative intent
Exclusion Criteria
- Induction chemotherapy - Pregnant and lactating women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility of H2O/O2 PET to determine changes in oxygen consumption and tumor hypoxia.
- Secondary Outcome Measures
Name Time Method Applicability of H2O/O2-PET/CT and biomarker analysis for hypoxia-adapted treatment planning, therapy monitoring and prognosis