KCT0008155招募中未知
Clinical efficacy of ctDNA dynamics before and after total neoadjuvant treatment in locally adjuvant rectal cancer.
Chonnam National University Hospital Hwasun Hospital0 个研究点目标入组 45 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational Study
入排标准
- 年龄范围
- 18(Year) 至 80(Year)（—）
- 性别
- All
入选标准
- •Histologically confirmed loco-regional rectal adenocarcinoma (cT3-4,Nany)
- •Male and female participants >=18 and <=80 of age inclusive, at the time of signing the informed consent
- •Radiologically confirmed cT3, CRM positive or T4 or unresectable in rectal MRI(enhance)
排除标准
- •Structurally bowel obstruction lesion or impending feature
- •bowel perforation or grade >= hemorrhage or bleeding event
- •History of distant metastatic lesions
- •Grade >=1 of CTC-AE
- •Uncontrolled significant cardiovascular disease or unstable angina or myocardial infarction or unstable arrhythmia or hepatitis or coagulopathy risk or psychosis prior to initiation of study treatment
- •Known allergy or hypersensitivity to fluoropyrimidine or platinum drugs or their excipients
- •Known DPD deficiency identified
- •Prior clinical study within 4 weeks prior to initiation of study treatment
研究者
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