Beetroot Extract and Its Influence on Cardiovascular and Autonomic Recovery From the Effort in Healthy Males

Not Applicable

Completed

• Conditions: Healthy Males
• Interventions: Dietary Supplement: Beetroot extract

• Registration Number: NCT05294198
• Lead Sponsor: University of Pernambuco

Brief Summary

There is no evidence that beetroot extract (Beta vulgaris L.) is advantageous for the recovery of cardiovascular parameters and the autonomic nervous system (ANS) after submaximal aerobic exercise. The objective of this study is to evaluate the effect of beetroot extract supplementation on the recovery of cardiorespiratory and autonomic parameters after a submaximal aerobic exercise session. Healthy male adults will perform a cross-over, randomized, double-blind, and placebo-controlled trial. Beetroot extract (600mg) or placebo (600mg) will be ingested 90 minutes before evaluation in randomized days. Systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), mean arterial pressure (MAP), heart rate (HR), and HR variability (HRV) indexes will be recorded at Rest and during 60 minutes of recovery from exercise.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-10
• Primary Completion: 2021-11-12
• Study Completion: 2021-11-12
• Status Verified: 2022-03
• Study First Submitted: 2022-03-04
• Study First Submitted QC: 2022-03-14
• Last Update Submitted: 2022-03-14
• Study First Posted: 2022-03-24
• Last Update Posted: 2022-03-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 16

Inclusion Criteria

• Healthy males;
• Physically active according to International Physical Activity Questionnaire (IPAQ);
• 18 to 30 old years.

Exclusion Criteria

• Body mass index BMI <18.5kg/m² and >29.9kg/m²;
• Smokers;
• Subjects undergoing pharmacotherapies;
• Musculoskeletal, metabolic, renal diseases;
• Root mean squared standard deviation of R-R intervals <15 milliseconds.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Beet protocol	Beetroot extract	Beta vulgaris L. extract (600mg)
Placebo protocol	Beetroot extract	Starch (600mg)

Primary Outcome Measures

Name	Time	Method
Heart rate variability values (milliseconds)	Through study completion, an average of 1 year

Secondary Outcome Measures

Name	Time	Method
Heart rate values (beats per minute)	Through study completion, an average of 1 year
Systolic and diastolic blood pressure values (mmHg)	Through study completion, an average of 1 year

Trial Locations

Locations (1)

University of Pernambuco; 🇧🇷 Petrolina, Pernambuco, Brazil