Clinical trial for the control of osteonecrosis of the femoral head secondary to the initial corticosteroid treatment in patients with systemic lupus erythematosus - Control of steroid-induced osteonecrosis of the femoral head in SLE patients

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University0 sites150 target enrollmentJune 22, 2012

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Systemic lupus erythematosus
Sponsor: Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
Enrollment: 150
Status: Recruiting
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

June 22, 2012

End Date

August 1, 2016

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University

•A. Objectives have never had corticosteroid treatment before the entry to the trial. B. Objectives have never been affected with osteonecrosis of the femoral head. C. Patients with any active bleeding lesion. D. Patients with any active infection. E. Patients have any contraindication to candidate drugs for the prevention. F. Patients have any past histories of anaphylaxis to candidate drugs for the prevention. G. Female in pregnancy, lactation period, having a possibility of pregnancy. H. Patients taking below contraindicative drugs. 1\. antiplatelet drugs expect clopidogrel 2\. anticoagulant 3\. cyclosporine 4\. fibrates I. Patients that have contraindication for MRI. J. Patients that are considered unsuitable for the entry to the trial.