Comparison outcomes between open surgery with or without local corticosteroid injection in De Quervain tenosynovitis

Phase 2

Completed

• Conditions: De Quervain' s tenosynovitis is a stenosing tenosynovitis of the first dorsal compartment of the wrist and leads to wrist pain and to impaired function of the wrist and hand. Surgical released remain gold standard treatment and show good outcome in long term.; De Quervain tenosynovitis, Surgery, Corticosteroid injection, adjunct therapy, Pain control, De Quervain release

• Registration Number: TCTR20230116001
• Lead Sponsor: Orthopedic police general hospital

Brief Summary

adjunct intraoperative local corticosteroid injection (group A) was significantly lower in the mean post-operative VAS scores at three days, one week, and two weeks. Furthermore, the mean post-operative QuickDASH scores were also significantly lower at one week and two weeks, compared with open surgery alone (group B) (p below 0.05). However, there was no statistically significant difference in mean VAS or QuickDASH scores between the two groups at four weeks and six weeks of follow-up assessments.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-05-31
• Study Start: 2023-01-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Pain and tenderness over the first dorsal compartment and a positive sign of Finkelstein test despite a minimum of 3 months non-operative treatment, including rest, splinting, and steroid injection.

Exclusion Criteria

(1) Patients had secondary arthritis to the wrist (related to rheumatoid arthritis, gouty arthritis, or post-infectious arthritis), (2) Patients had previous traumatic injury to the wrist, (3) Patients had allergic to medicines used in this study (Kenacort-40), (4) Patients with uncontrolled diabetes (HbA1C > 7.0), (5) patients were involved with other symptomatic upper limb disorders, such as adhesive capsulitis, rotator cuff tear, lateral epicondylitis, and carpal tunnel syndrome etc. and (6) patients who have had steroid injections in the same wrist within 6 weeks before surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS score 3,7,14,28,42 days Visual Analogue Scale score

Secondary Outcome Measures

Name	Time	Method
QuickDASH 7,14,28,42 days The Qucik disabilities of the arm, shoulder and hand score