临床试验/NCT01269541

NCT01269541已完成不适用

MESS- MRSA Eradication Study Skåne. A Comparison Between Systemic Antibiotic Treatment in Combination With Topical Mupirocintreatment With Only Topical Mupiroicintreatment to Eradicate MRSA in Throat Carriers

Region Skane6 个研究点分布在 1 个国家目标入组 69 人开始时间: 2011年3月1日最近更新: 2017年8月22日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: Region Skane
入组人数: 69
试验地点: 6
主要终点: Culture for MRSA

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine whether systemic antibiotic treatment with rifampicin and clindamycine or trimethoprim-sulfa in addition to topical treatment with mupirocin is more effective than only topical treatment to eradicate MRSA in throatcarriers

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: 5 Years 至 —（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Colonized with MRSA in the throat Older than 5 years MRSA-bacteria sensitive for Rifampicin and Clindamycine or Trimethoprimsulfa -

排除标准

•Allergy to the studymedication Healthcareworkers Pregnancy Active infection with MRSA Immunosuppression Treatment with other antibiotic during the studyperiod

研究组 & 干预措施

Mupirocin

Active Comparator

Topical treatment

干预措施: Mupirocin (Drug)

Mupirocin

Active Comparator

Topical treatment

干预措施: Rifampin+Clindamycine or Trimehoprimsulfa (Drug)

Rifampicin+Clindamycine or Trimethoprimsulfa

Active Comparator

Rifampicin 10 mg/kgx1xVII Clindamycine 300 mgx3xVII Trimethoprimsulfa 400mg/80mg 2x2

干预措施: Rifampin+Clindamycine or Trimehoprimsulfa (Drug)

结局指标

主要结局

Culture for MRSA

时间窗: after 6 months

次要结局

未报告次要终点

研究者

发起方

Region Skane

申办方类型

Other

责任方

Sponsor

研究点 (6)

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