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Clinical Trials/NCT06325371
NCT06325371
Recruiting
Not Applicable

Italian Multicentric Study on the Treatment of Visceral Aneurysms With the Flow Diversion Stent Derivo Peripher and Derivo 2

University of Turin, Italy1 site in 1 country100 target enrollmentNovember 20, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aneurysm Abdominal
Sponsor
University of Turin, Italy
Enrollment
100
Locations
1
Primary Endpoint
Efficacy of the stenting in terms of aneurysm thrombosis rate
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This is a multicentric voluntary observational study with a retrospective evaluation of prospectively collected data concerning the treatment of visceral aneurysms with flow diversion stent Derivo Peripher and Derivo 2 (DED, Acandis GmbH) Follow-up will include clinical and radiological (CT) evaluation at least 12 months after the intervention.

The enrollment period will be of 65 months (01/jan/2020-30/jun/2025). Sample size will be of 100 patients.

Registry
clinicaltrials.gov
Start Date
November 20, 2024
End Date
June 30, 2026
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
University of Turin, Italy
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • patients who are hemodynamically unstable or show CT signs of rupture or contained rupture of visceral aneurysm
  • pregnant or breastfeeding women
  • life expectancy less than 2 years

Outcomes

Primary Outcomes

Efficacy of the stenting in terms of aneurysm thrombosis rate

Time Frame: 12 months

aneurysm (partial or complete, \>50% or 100%) thrombosis

Safety in terms of morbidity

Time Frame: 12 months

morbidity (any adverse events occured during follow up for any causes and by causes associated with treatment)

Safety in terms of mortality

Time Frame: 12 months

mortality (any cause of death related to pathology or not)

Safety in terms of technical issues

Time Frame: 12 months

technical issues (any adverse event during stent placement)

Efficacy of the stenting in terms of patency and side branches

Time Frame: 12 months

stent patency and side branches (the absence of stenosis greater than 50% of the stent's internal lumen and the side branches' lumen)

Efficacy of the stenting in terms of aneurysm volume assessment

Time Frame: 12 months

aneurysm volume assessment (percentage of volume reduction respect to the initial volume)

Study Sites (1)

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