Non-invasive Left-sided Cervical Vagus Nerve Stimulation for Atrioventricular Reentrant Tachycardia

Not Applicable

Recruiting

• Conditions: Atrioventricular Reentrant Tachycardia
• Interventions: Device: Non-invasive vagus nerve stimulation

• Registration Number: NCT06219343
• Lead Sponsor: Jingye Tai

Brief Summary

The goal of this Interventional clinical trials in atrioventricular reentrant tachycardia patients. The main question it aims to answer whether non-invasive vagus nerve stimulation could be effective in restoring rhythm.

Patients will receive non-invasive vagus nerve electrical stimulation under catheter evoked and cardiac monitoring to observe their heart rhythm changes.

Detailed Description

Participants will be treated with non-invasive electrical stimulation of the left vagus nerve in the neck. After routine induction of atrioventricular reentrant tachycardia prior to radiofrequency ablation, the electrode patch was placed on the patient's left cervical vagal body surface localization, i.e., between the sternocleidomastoid muscle and the trachea where the left common carotid artery pulsation could be palpated, and resuscitation was performed using non-invasive electrical stimulation.

Study Timeline

• Study Start: 2023-01-10
• Study First Submitted: 2023-12-27
• Status Verified: 2024-01
• Study First Submitted QC: 2024-01-12
• Last Update Submitted: 2024-01-12
• Study First Posted: 2024-01-23
• Last Update Posted: 2024-01-23
• Primary Completion: 2024-12-10
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. The relevant diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Supraventricular Tachycardia (svt) need to be met.
2. All need to be free of psychiatric abnormalities, verbal communication disorders, and have good compliance.
3. The patients and their families gave informed consent and signed the informed consent form.

Exclusion Criteria

1. Does not meet the relevant diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Supraventricular Tachycardia (svt).
2. Mental anomalies, verbal communication disorders, poor adherence
3. Those who do not consent to participate in this clinical trial

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Transcervical non-invasive vagus nerve stimulation group	Non-invasive vagus nerve stimulation	Patient will be treated with non-invasive electrical stimulation of the left vagus nerve in the neck. After routine induction of atrioventricular reentrant tachycardia prior to radiofrequency ablation, the electrode patch was placed on the patient's left cervical vagal body surface localization, i.e., between the sternocleidomastoid muscle and the trachea where the left common carotid artery pulsation could be palpated, and resuscitation was performed using non-invasive electrical stimulation.

Primary Outcome Measures

Name	Time	Method
Whether the tachycardia is repetitive or not	10minutes	Determining whether a tachycardia is reentrant on the basis of the ambulatory electrocardiogram

Secondary Outcome Measures

Name	Time	Method
Parameters leading to tachycardia resumption	10minutes	Intensity of electrical stimuli leading to tachycardia resumption

Trial Locations

Locations (1)

Ai-lan Chen; 🇨🇳 Guangzhou, Guangdong, China